日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis

阿那他宾可减轻葡聚糖硫酸钠诱导的小鼠结肠炎模型中的肠道炎症并减少促炎因子的产生。

Ruiz Castro, Pedro A; Kogel, Ulrike; Lo Sasso, Giuseppe; Phillips, Blaine W; Sewer, Alain; Titz, Bjorn; Garcia, Llenalia; Kondylis, Athanasios; Guedj, Emmanuel; Peric, Dariusz; Bornand, David; Dulize, Remi; Merg, Celine; Corciulo, Maica; Ivanov, Nikolai V; Peitsch, Manuel C; Hoeng, Julia

Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke

一项利用多组学系统毒理学方法研究小鼠肺部,评估两种加热不燃烧烟草制品和香烟烟雾气溶胶的影响。

Titz, Bjoern; Szostak, Justyna; Sewer, Alain; Phillips, Blaine; Nury, Catherine; Schneider, Thomas; Dijon, Sophie; Lavrynenko, Oksana; Elamin, Ashraf; Guedj, Emmanuel; Tsin Wong, Ee; Lebrun, Stefan; Vuillaume, Grégory; Kondylis, Athanasios; Gubian, Sylvain; Cano, Stephane; Leroy, Patrice; Keppler, Brian; Ivanov, Nikolai V; Vanscheeuwijck, Patrick; Martin, Florian; Peitsch, Manuel C; Hoeng, Julia

The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts

暴露于香烟烟雾的小鼠DSS诱导结肠炎严重程度的降低与免疫调节和微生物群落变化有关。

Lo Sasso, Giuseppe; Phillips, Blaine W; Sewer, Alain; Battey, James N D; Kondylis, Athanasios; Talikka, Marja; Titz, Bjoern; Guedj, Emmanuel; Peric, Dariusz; Bornand, David; Dulize, Remi; Merg, Celine; Corciulo, Maica; Ouadi, Sonia; Yanuar, Rendy; Tung, Ching Keong; Ivanov, Nikolai V; Peitsch, Manuel C; Hoeng, Julia

A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products

一项关于人类呼吸消化道上皮细胞培养物中表达的microRNA及其作为尼古丁产品暴露反应潜在生物标志物的荟萃分析

Sewer, Alain; Zanetti, Filippo; Iskandar, Anita R; Guedj, Emmanuel; Dulize, Remi; Peric, Dariusz; Bornand, David; Mathis, Carole; Martin, Florian; Ivanov, Nikolai V; Peitsch, Manuel C; Hoeng, Julia

Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract

构建一套以呼吸道黏液纤毛清除为重点的可计算生物网络模型

Yepiskoposyan, Hasmik; Talikka, Marja; Vavassori, Stefano; Martin, Florian; Sewer, Alain; Gubian, Sylvain; Luettich, Karsta; Peitsch, Manuel Claude; Hoeng, Julia

Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach

候选改良风险烟草产品气溶胶和香烟烟雾对人类类器官小气道培养物的比较效应:系统毒理学方法

Iskandar, Anita R; Martinez, Yannick; Martin, Florian; Schlage, Walter K; Leroy, Patrice; Sewer, Alain; Torres, Laura Ortega; Majeed, Shoaib; Merg, Celine; Trivedi, Keyur; Guedj, Emmanuel; Frentzel, Stefan; Mathis, Carole; Ivanov, Nikolai V; Peitsch, Manuel C; Hoeng, Julia

Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models

利用双层因果模型量化生物网络扰动,以深入了解其机制并进行诊断

Martin, Florian; Sewer, Alain; Talikka, Marja; Xiang, Yang; Hoeng, Julia; Peitsch, Manuel C

Assessment of a novel multi-array normalization method based on spike-in control probes suitable for microRNA datasets with global decreases in expression

评估一种基于外源对照探针的新型多阵列归一化方法,该方法适用于表达量整体下降的microRNA数据集。

Sewer, Alain; Gubian, Sylvain; Kogel, Ulrike; Veljkovic, Emilija; Han, Wanjiang; Hengstermann, Arnd; Peitsch, Manuel C; Hoeng, Julia

An algorithm for score aggregation over causal biological networks based on random walk sampling

一种基于随机游走抽样的因果生物网络评分聚合算法

Vasilyev, Dmitry M; Thomson, Ty M; Frushour, Brian P; Martin, Florian; Sewer, Alain

Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model

系统毒理学方法能够对A/J小鼠模型中自发性肺肿瘤和香烟烟雾相关肺肿瘤的发生机制进行比较。

Luettich, Karsta; Xiang, Yang; Iskandar, Anita; Sewer, Alain; Martin, Florian; Talikka, Marja; Vanscheeuwijck, Patrick; Berges, An; Veljkovic, Emilija; Gonzalez-Suarez, Ignacio; Schlage, Walter; Hoeng, Julia; Peitsch, Manuel