Genome-wide antibiotic-CRISPRi profiling identifies LiaR activation as a strategy to resensitize fluoroquinolone-resistant Streptococcus pneumoniae.
全基因组抗生素 CRISPRi 分析发现 LiaR 激活是使耐氟喹诺酮类肺炎链球菌重新敏感的策略
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-61814-x
Sewgoolam Bevika, Jim Kin Ki, de Bakker Vincent, Bock Florian P, Gibson Paddy S, Veening Jan-Willem
