日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

谱系特异性基因组结构将增强子和非编码疾病变异与靶基因启动子联系起来

Biola M Javierre ,Oliver S Burren ,Steven P Wilder ,Roman Kreuzhuber ,Steven M Hill ,Sven Sewitz ,Jonathan Cairns ,Steven W Wingett ,Csilla Várnai ,Michiel J Thiecke ,Frances Burden ,Samantha Farrow ,Antony J Cutler ,Karola Rehnström ,Kate Downes ,Luigi Grassi ,Myrto Kostadima ,Paula Freire-Pritchett ,Fan Wang ,John A Todd ,Daniel R Zerbino ,Oliver Stegle ,Willem H Ouwehand ,Mattia Frontini ,Chris Wallace ,Mikhail Spivakov ,Peter Fraser

An integrated model of transcription factor diffusion shows the importance of intersegmental transfer and quaternary protein structure for target site finding

转录因子扩散的整合模型表明,片段间转移和蛋白质四级结构对于靶位点的寻找至关重要。

Schmidt, Hugo G; Sewitz, Sven; Andrews, Steven S; Lipkow, Karen

A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression

一种能破坏G-四链体DNA结构并增强基因表达的小分子

Waller, Zoë A E; Sewitz, Sven A; Hsu, Shang-Te Danny; Balasubramanian, Shankar

Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression

三取代异咯嗪作为一类新型G-四链体结合配体:小分子调控c-kit癌基因表达

Bejugam, Mallesham; Sewitz, Sven; Shirude, Pravin S; Rodriguez, Raphaël; Shahid, Ramla; Balasubramanian, Shankar

Characterization of the aes gene of Escherichia coli encoding an enzyme with esterase activity

对大肠杆菌中编码具有酯酶活性的酶的aes基因进行表征

Peist, R; Koch, A; Bolek, P; Sewitz, S; Kolbus, T; Boos, W