文献库，生知库 | 链接生命科学的每一步

Krebs, Catharine E; Camp, Celean; Constantino, Helder; Courtot, Lilas; Kavanagh, Owen; McCarthy, Janine; Ort, Melanie-Jasmin; Sarasija, Shaarika; Trunnell, Emily R

发表日期：2023

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The Role of Neuroglial Metabotropic Glutamate Receptors in Alzheimer's Disease

神经胶质代谢型谷氨酸受体在阿尔茨海默病中的作用

期刊:Current Neuropharmacology

影响因子:5.3

doi:10.2174/1570159X19666210916102638

Abd-Elrahman, Khaled S; Sarasija, Shaarika; Ferguson, Stephen S G

A positive allosteric modulator for the muscarinic receptor (M1 mAChR) improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice

毒蕈碱受体 (M1 mAChR) 的正向变构调节剂可改善雌性 APPswe/PSEN1ΔE9 小鼠的病理和认知缺陷

期刊:British Journal of Pharmacology

影响因子:6.8

doi:10.1111/bph.15750

Khaled S Abd-Elrahman, Shaarika Sarasija, Tash-Lynn L Colson, Stephen S G Ferguson

信号转导

发表日期：2022

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Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration

早老素缺失导致线粒体钙摄取增加和线粒体活性增强，进而促进 mTORC1 信号通路，驱动神经退行性变。

期刊:Aging Cell

影响因子:7.1

doi:10.1111/acel.13472

Ryan, Kerry C; Ashkavand, Zahra; Sarasija, Shaarika; Laboy, Jocelyn T; Samarakoon, Rohan; Norman, Kenneth R

Corrupted ER-mitochondrial calcium homeostasis promotes the collapse of proteostasis

内质网-线粒体钙稳态紊乱会促进蛋白质稳态崩溃。

期刊:Aging Cell

影响因子:7.1

doi:10.1111/acel.13065

Ashkavand, Zahra; Sarasija, Shaarika; Ryan, Kerry C; Laboy, Jocelyn T; Norman, Kenneth R

Measurement of Oxygen Consumption Rates in Intact Caenorhabditis elegans

完整秀丽隐杆线虫耗氧率的测量

期刊:Jove-Journal of Visualized Experiments

影响因子:1

doi:10.3791/59277

Sarasija, Shaarika; Norman, Kenneth R

C. elegans

发表日期：2019

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Role of Presenilin in Mitochondrial Oxidative Stress and Neurodegeneration in Caenorhabditis elegans

早老素在秀丽隐杆线虫线粒体氧化应激和神经退行性变中的作用

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox7090111

Sarasija, Shaarika; Norman, Kenneth R

Presenilin mutations deregulate mitochondrial Ca(2+) homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans

早老素基因突变会扰乱线虫线粒体Ca(2+)稳态和代谢活动，导致线虫神经退行性变。

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.33052

Sarasija, Shaarika; Laboy, Jocelyn T; Ashkavand, Zahra; Bonner, Jennifer; Tang, Yi; Norman, Kenneth R

Analysis of Mitochondrial Structure in the Body Wall Muscle of Caenorhabditis elegans

秀丽隐杆线虫体壁肌肉线粒体结构分析

期刊:Bio-protocol

影响因子:1

doi:10.21769/BioProtoc.2801

Shaarika Sarasija, Kenneth R Norman

微生物学

发表日期：2018

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Measurement of ROS in Caenorhabditis elegans Using a Reduced Form of Fluorescein

使用还原形式的荧光素测量秀丽隐杆线虫中的 ROS

期刊:Bio-protocol

影响因子:1

doi:10.21769/BioProtoc.2800

Shaarika Sarasija, Kenneth R Norman

微生物学

发表日期：2018

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Author Guide for Addressing Animal Methods Bias in Publishing

作者指南：如何应对出版中的动物实验方法偏见

The Role of Neuroglial Metabotropic Glutamate Receptors in Alzheimer's Disease

神经胶质代谢型谷氨酸受体在阿尔茨海默病中的作用

A positive allosteric modulator for the muscarinic receptor (M1 mAChR) improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice

毒蕈碱受体 (M1 mAChR) 的正向变构调节剂可改善雌性 APPswe/PSEN1ΔE9 小鼠的病理和认知缺陷

Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration

早老素缺失导致线粒体钙摄取增加和线粒体活性增强，进而促进 mTORC1 信号通路，驱动神经退行性变。

Corrupted ER-mitochondrial calcium homeostasis promotes the collapse of proteostasis

内质网-线粒体钙稳态紊乱会促进蛋白质稳态崩溃。

Measurement of Oxygen Consumption Rates in Intact Caenorhabditis elegans

完整秀丽隐杆线虫耗氧率的测量

Role of Presenilin in Mitochondrial Oxidative Stress and Neurodegeneration in Caenorhabditis elegans

早老素在秀丽隐杆线虫线粒体氧化应激和神经退行性变中的作用

Presenilin mutations deregulate mitochondrial Ca(2+) homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans

早老素基因突变会扰乱线虫线粒体Ca(2+)稳态和代谢活动，导致线虫神经退行性变。

Analysis of Mitochondrial Structure in the Body Wall Muscle of Caenorhabditis elegans

秀丽隐杆线虫体壁肌肉线粒体结构分析

Measurement of ROS in Caenorhabditis elegans Using a Reduced Form of Fluorescein

使用还原形式的荧光素测量秀丽隐杆线虫中的 ROS