Oral administration of non-absorbable delayed release 6-mercaptopurine is locally active in the gut, exerts a systemic immune effect and alleviates Crohn's disease with low rate of side effects: results of double blind Phase II clinical trial
口服不可吸收的缓释型6-巯基嘌呤可在肠道局部发挥作用，产生全身免疫效应，并能缓解克罗恩病，且副作用发生率低：双盲II期临床试验结果
期刊:Clinical and Experimental Immunology
影响因子:3.8
doi:10.1111/cei.12640
Israeli, E; Goldin, E; Fishman, S; Konikoff, F; Lavy, A; Chowers, Y; Melzer, E; Lahat, A; Mahamid, M; Shirin, H; Nussinson, E; Segol, O; Ya'acov, A Ben; Shabbat, Y; Ilan, Y
