Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy
表皮生长因子受体 (EGFR) 的转录受 Y 盒结合蛋白-1 (YB-1) 的诱导,并且在基底样乳腺癌中可被易瑞沙抑制,这为治疗提供了一个潜在的靶点。
期刊:Breast Cancer Research
影响因子:5.6
doi:10.1186/bcr1767
Stratford, Anna L; Habibi, Golareh; Astanehe, Arezoo; Jiang, Helen; Hu, Kaiji; Park, Eugene; Shadeo, Ashleen; Buys, Timon P H; Lam, Wan; Pugh, Trevor; Marra, Marco; Nielsen, Torsten O; Klinge, Uwe; Mertens, Peter R; Aparicio, Samuel; Dunn, Sandra E