日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Bifunctional Small Molecule Degrader of the Long Noncoding RNA MALAT1 Triplex

一种双功能小分子降解剂,可降解长链非编码RNA MALAT1三链体。

Brega, Christian A T; Craig, Benjamin A; Mikutis, Sigitas; Proctor, Rupert S J; Vyborna, Yuliia; Ivey, Galway; Eleftheriou, Maria; Tzelepis, Kostas; Yang, Mo; Parmar, Shaifaly; Bonet-Aleta, Javier; Schneekloth, John S Jr; Bernardes, Gonçalo J L

Harnessing Molecular Recognition for Small-Molecule-Mediated Reversible Photochemical Control Over mRNA Translation

利用分子识别实现小分子介导的对mRNA翻译的可逆光化学控制

Parmar, Shaifaly; Tenney, Logan; Liang, Xiao; Routzahn, John T 4th; Sibley, Christopher D; Schneekloth, John S Jr

Discovery of small molecule probes targeting the 5' stem-loop in the yeast U4/U6 snRNA

发现靶向酵母U4/U6 snRNA 5'茎环的小分子探针

Yang, Mo; Parmar, Shaifaly; Balaratnam, Sumirtha; Bume, Desta D; Prestwood, Peri R; Kasprzak, Wojciech K; Schneekloth, John S Jr

Mechanistic analysis of Riboswitch Ligand interactions provides insights into pharmacological control over gene expression

对核糖开关配体相互作用的机制分析为基因表达的药理学调控提供了新的见解

Parmar, Shaifaly; Bume, Desta Doro; Connelly, Colleen M; Boer, Robert E; Prestwood, Peri R; Wang, Zhen; Labuhn, Henning; Sinnadurai, Krishshanthi; Feri, Adeline; Ouellet, Jimmy; Homan, Philip; Numata, Tomoyuki; Schneekloth, John S Jr

Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression

核糖开关配体相互作用的机制分析为基因表达的药理学调控提供了新的见解

Parmar, Shaifaly; Bume, Desta Doro; Conelly, Colleen; Boer, Robert; Prestwood, Peri R; Wang, Zhen; Labuhn, Henning; Sinnadurai, Krishshanthi; Feri, Adeline; Ouellet, Jimmy; Homan, Philip; Numata, Tomoyuki; Schneekloth, John S Jr

Interrogating RNA-Small Molecule Interactions with Structure Probing and Artificial Intelligence-Augmented Molecular Simulations

利用结构探测和人工智能增强的分子模拟研究RNA-小分子相互作用

Wang, Yihang; Parmar, Shaifaly; Schneekloth, John S; Tiwary, Pratyush

Targeting a noncanonical, hairpin-containing G-quadruplex structure from the MYCN gene

靶向 MYCN 基因中含有发夹结构的非典型 G-四链体结构

Mo Yang, Sakereh Carter, Shaifaly Parmar, Desta D Bume, David R Calabrese, Xiao Liang, Kamyar Yazdani, Man Xu, Zhihui Liu, Carol J Thiele, John S Schneekloth

Identification and expression analysis of miRNAs and elucidation of their role in salt tolerance in rice varieties susceptible and tolerant to salinity

对水稻品种中易感盐胁迫和耐盐胁迫的miRNA进行鉴定和表达分析,并阐明其在耐盐性中的作用

Parmar, Shaifaly; Gharat, Sachin Ashruba; Tagirasa, Ravichandra; Chandra, Tilak; Behera, Lambodar; Dash, Sushant Kumar; Shaw, Birendra Prasad

The Anterolateral Ligament of the Knee: Descriptive Anatomy and Clinical Correlation

膝关节前外侧韧带:解剖学描述及临床相关性

Rustagi, Shaifaly Madan; Gopal, Parikshat; Ahuja, Manish Singh; Arora, Naresh Chander; Sood, Nikhil

Transcriptome Analysis of the Response to NaCl in Suaeda maritima Provides an Insight into Salt Tolerance Mechanisms in Halophytes

对盐蓬(Suaeda maritima)响应NaCl的转录组分析揭示了盐生植物的耐盐机制

Gharat, Sachin Ashruba; Parmar, Shaifaly; Tambat, Subodh; Vasudevan, Madavan; Shaw, Birendra Prasad