SARS-CoV-2 infection in hiPSC-derived neurons is cathepsin-dependent and causes differential accumulation of HIF1É and phosphorylated tau.
SARS-CoV-2 感染 hiPSC 衍生的神经元是组织蛋白酶依赖性的，并导致 HIF1É' 和磷酸化 tau 的差异性积累。
期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102726
Kettunen Pinja, Ruuska Janika, Quirin Tania, Ojha Ravi, Saber Saber H, Sng Julian D J, Morrison Sean, Al-Mhanawi Bahaa, Shaker Mohammed R, De Neck Simon, Kipar Anja, Paavolainen Lassi, Wolvetang Ernst, Joensuu Merja, Koistinaho Jari, Rolova Taisia, Balistreri Giuseppe
