A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding
一种在肿瘤细胞和多能干细胞中表达的新型DNMT3B剪接变体能够调节基因组DNA甲基化模式并改变DNA结合能力。
期刊:Molecular Cancer Research
影响因子:4.7
doi:10.1158/1541-7786.MCR-09-0018
Gopalakrishnan, Suhasni; Van Emburgh, Beth O; Shan, Jixiu; Su, Zhen; Fields, C Robert; Vieweg, Johannes; Hamazaki, Takashi; Schwartz, Philip H; Terada, Naohiro; Robertson, Keith D
肿瘤
表观遗传
肿瘤免疫
细胞生物学
DNA甲基化
干细胞
发育与干细胞
肿瘤细胞