Shan-Han相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Tumour-infiltrating microplastics disrupt the JAK-STAT-microbiota axis to promote immunotherapy resistance in colorectal cancer.

肿瘤浸润性微塑料会破坏 JAK-STAT-微生物群轴，从而促进结直肠癌的免疫治疗耐药性。

期刊:Molecular Cancer

影响因子:33.9

doi:10.1186/s12943-026-02588-8

Jiang Zhaohui, Liu Yongting, Zhang Peng, Fei Jiang, Wang Kailing, Li Yin, Zhang Xiangyang, Cai Changjing, Chen Yihong, Peng Yinghui, Shen Hong, Zeng Shan, Han Ying

发表日期：2026

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Female reproductive tract-on-a-chip for selecting sperm with ultra-low DNA fragmentation index.

用于筛选DNA碎片指数超低的精子的女性生殖道芯片。

期刊:Microsystems & Nanoengineering

影响因子:9.9

doi:10.1038/s41378-026-01165-9

Dai Jing, Shan Han, Gu Yifan, Zheng Mingde, Lou Li, Xie Pingyuan, Zhang Shen, Sun Zheng, Gong Fei, Lu Guangxiu, Lin Ge, Chen Zeyu

发表日期：2026

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SpiroLLM: Finetuning pretrained LLMs to understand spirogram time series with clinical validation in COPD reporting

SpiroLLM：通过微调预训练的LLM模型来理解肺活量图时间序列，并在COPD报告中进行临床验证

期刊:PLOS Digital Health

影响因子:7.7

doi:10.1371/journal.pdig.0001300

Mei, Shuhao; Long, Yongchao; Xiao, Xiaoyu; Cao, Shan; Han, Xiaobo; Geng, Shijia; Sun, Jinbo; Zhou, Yuxi; Hong, Shenda

慢性阻塞性肺疾病

发表日期：2026

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Preclinical activity of SHR-A1921, a novel antibody-drug conjugate targeting trophoblast cell-surface antigen2 (Trop-2) in prostate cancer

SHR-A1921是一种新型抗体药物偶联物，靶向滋养层细胞表面抗原2 (Trop-2)，在前列腺癌中的临床前活性

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2026.1713983

Wang, Binyu; Xu, Qiuya; Peng, Shan; Han, Zheng; Huang, Haifeng; Guo, Hongqian; Qiu, Xuefeng

细胞生物学

发表日期：2026

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MUC14 suppresses lung adenocarcinoma via integrin α8β6/PI3K/AKT/MAPK modulating cisplatin response and immunity

MUC14通过整合素α8β6/PI3K/AKT/MAPK通路调节顺铂反应和免疫反应，从而抑制肺腺癌。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-026-39019-z

Li, Xiaoqing; Li, Ming; Huang, Shizhuan; Zhang, Zhihua; Xing, Chen; Yu, Shan; Han, Guiping

免疫/内分泌

发表日期：2026

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Metagenomic next-generation sequencing for efficient detection of human parvovirus B19 in amniotic fluid: a case study of diagnosis and prenatal management of fetal infection

利用宏基因组二代测序技术高效检测羊水中人细小病毒B19：以胎儿感染的诊断和产前管理为例

期刊:BMC Pregnancy and Childbirth

影响因子:2.7

doi:10.1186/s12884-026-08743-9

Ma, Ruiyu; Sun, Jinling; Zhu, Jing; Wu, Yi; Shi, Yiru; Yang, Yunfan; Wang, Shan; Han, Xu; Li, Shuyuan; Gao, Li; Zhao, Xinrong; Hua, Renyi; Wang, Yanlin

发表日期：2026

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Calcifying fibrous tumors of the thoracic cavity: a clinicopathological series of seven solitary cases

胸腔钙化性纤维瘤：7例孤立病例的临床病理系列研究

期刊:Diagnostic Pathology

影响因子:2.3

doi:10.1186/s13000-026-01780-0

Lou, Ge; Xing, Chen; Zhang, Yujie; Yu, Shan; Han, Guiping

发表日期：2026

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Drug-related problems in pediatric patients with chronic kidney disease: A single-center prospective study

儿童慢性肾脏病患者药物相关问题：一项单中心前瞻性研究

doi:10.3892/etm.2026.13102

Liu, Xingxing; Li, Yue; Mao, Zhen; Wang, Xin; Zhao, Shan; Han, Qiu; Liu, Jia; Zhou, Yan; Li, Shi; Chen, Bing; Hang, Yongfu; Yan, Wan; Jin, Xiaoye

发表日期：2026

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MS4A6A/Ms4a6d deficiency disrupts neuroprotective microglia functions and promotes inflammation in Alzheimer's disease model

MS4A6A/Ms4a6d 缺陷会破坏神经保护性小胶质细胞功能，并促进阿尔茨海默病模型中的炎症反应。

期刊:Molecular Neurodegeneration

影响因子:14.9

doi:10.1186/s13024-025-00887-0

Hai-Shan Jiao ，Yi-Jun Ge ，Liang-Yu Huang ，Ying Liu ，Bang-Sheng Wu ，Piao-Piao Lian ，Yi-Ning Hao ，Shan-Shan Han ，Yi-Ting Li ，Kai-Min Wu ，Chen-Yun Wu ，Tian-Lin Cheng ，Peng Yuan ，Jin-Tai Yu

细胞生物学

多发性硬化症

阿尔茨海默症

发表日期：2025

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PRMT5 Inhibitor Synergizes with Chemotherapy to Induce Resembling Mismatch Repair Deficiency and Enhance Anti-TIGIT Therapy in Microsatellite-Stable Colorectal Cancer

PRMT5抑制剂与化疗协同作用，诱导类似错配修复缺陷的基因表达，并增强微卫星稳定型结直肠癌中抗TIGIT疗法的疗效

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202500271

Zhu, Jiang; Fu, Shenao; Zou, Xi; Zeng, Hanjiang; Cui, Guangzu; Peng, Yinghui; Tang, Diya; Zhang, Fan; Shen, Hong; Zeng, Shan; Han, Ying

发表日期：2025

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