Shane M Harding相关文献与解析，生知库 | 链接生命科学的每一步

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness

代谢酶己糖激酶2在急性髓系白血病（AML）和正常造血干细胞及祖细胞中定位于细胞核内，以维持干性。

Geethu Emily Thomas # ，Grace Egan # ，Laura García-Prat ，Aaron Botham ，Veronique Voisin ，Parasvi S Patel ，Fieke W Hoff ，Jordan Chin ，Boaz Nachmias ，Kerstin B Kaufmann ，Dilshad H Khan ，Rose Hurren ，Xiaoming Wang ，Marcela Gronda ，Neil MacLean ，Cristiana O'Brien ，Rashim P Singh ，Courtney L Jones ，Shane M Harding ，Brian Raught ，Andrea Arruda ，Mark D Minden ，Gary D Bader ，Razq Hakem ，Steve Kornblau ，John E Dick ，Aaron D Schimmer

代谢

Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses

细胞周期检查点协同抑制 DNA 和 RNA 相关分子模式识别和抗肿瘤免疫反应

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2020.108080

Jie Chen, Shane M Harding, Ramakrishnan Natesan, Lei Tian, Joseph L Benci, Weihua Li, Andy J Minn, Irfan A Asangani, Roger A Greenberg

Mitotic progression following DNA damage enables pattern recognition within micronuclei

DNA 损伤后的有丝分裂进程使微核内的模式识别成为可能

期刊:Nature

影响因子:50.5

doi:10.1038/nature23470

Shane M Harding, Joseph L Benci, Jerome Irianto, Dennis E Discher, Andy J Minn, Roger A Greenberg

信号转导

发表日期：2017

文献求助收藏

DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities

DNA 双链断裂修复途径的选择由不同的 MRE11 核酸酶活性决定

期刊:Molecular Cell

影响因子:14.5

doi:10.1016/j.molcel.2013.11.003

Atsushi Shibata, Davide Moiani, Andrew S Arvai, Jefferson Perry, Shane M Harding, Marie-Michelle Genois, Ranjan Maity, Sari van Rossum-Fikkert, Aryandi Kertokalio, Filippo Romoli, Amani Ismail, Ermal Ismalaj, Elena Petricci, Matthew J Neale, Robert G Bristow, Jean-Yves Masson, Claire Wyman, Penny A

信号转导

发表日期：2014

文献求助收藏

Discordance between phosphorylation and recruitment of 53BP1 in response to DNA double-strand breaks

DNA 双链断裂后 53BP1 的磷酸化和募集不一致

期刊:Cell Cycle

影响因子:3.4

doi:10.4161/cc.19824

Shane M Harding, Robert G Bristow

表观遗传

发表日期：2012

文献求助收藏

Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage

在外源性 DNA 损伤位点，p53 磷酸化形式与 ATM 和 53BP1 之间发生蛋白质-蛋白质相互作用

期刊:Radiation Research

影响因子:2.5

doi:10.1667/RR2084.1

Shahnaz T Al Rashid, Shane M Harding, Cindy Law, Carla Coackley, Robert G Bristow

表观遗传

发表日期：2011

文献求助收藏

The proteomic landscape of genotoxic stress-induced micronuclei

基因毒性应激诱导的微核的蛋白质组学图景

Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei

先前染色质的组织决定了 cGAS 向破裂微核的募集

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness

代谢酶己糖激酶2在急性髓系白血病（AML）和正常造血干细胞及祖细胞中定位于细胞核内，以维持干性。

Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses

细胞周期检查点协同抑制 DNA 和 RNA 相关分子模式识别和抗肿瘤免疫反应

Mitotic progression following DNA damage enables pattern recognition within micronuclei

DNA 损伤后的有丝分裂进程使微核内的模式识别成为可能

DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities

DNA 双链断裂修复途径的选择由不同的 MRE11 核酸酶活性决定

Discordance between phosphorylation and recruitment of 53BP1 in response to DNA double-strand breaks

DNA 双链断裂后 53BP1 的磷酸化和募集不一致

Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage

在外源性 DNA 损伤位点，p53 磷酸化形式与 ATM 和 53BP1 之间发生蛋白质-蛋白质相互作用