Cyanoglycosides isolated from Moringa oleifera seeds inhibited PFKFB3/TGF-β1/smads pathway to alleviate diabetic nephropathy through driving metabolic reprogramming.
从辣木种子中分离出的氰苷通过驱动代谢重编程抑制PFKFB3/TGF-β1/smads通路，从而缓解糖尿病肾病。
期刊:Pharmaceutical Biology
影响因子:4.8
doi:10.1080/13880209.2025.2607563
Ge Chengyu, Shi Zhihua, He Jia, Feng Xu, Shang Kaiqi, Liao Xiaolin, Liu Yufeng, Jiang Yueping, Liu Shao
信号转导
代谢
代谢重编程
TGF-β1
PFKFB3
糖尿病
糖尿病肾病
