Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
特定 MDM2 抑制剂暂时激活 p53 对肿瘤具有选择性毒性,并导致肿瘤生长完全抑制
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.0708917105
Sanjeev Shangary, Dongguang Qin, Donna McEachern, Meilan Liu, Rebecca S Miller, Su Qiu, Zaneta Nikolovska-Coleska, Ke Ding, Guoping Wang, Jianyong Chen, Denzil Bernard, Jian Zhang, Yipin Lu, Qingyang Gu, Rajal B Shah, Kenneth J Pienta, Xiaolan Ling, Sanmao Kang, Ming Guo, Yi Sun, Dajun Yang, Shaomen