Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidation
靶向选择性PCK1和PGC-1α赖氨酸乙酰化的小分子通过增加乳酸氧化发挥抗糖尿病作用。
期刊:Cell Chemical Biology
影响因子:7.2
doi:10.1016/j.chembiol.2025.01.005
Mutlu, Beste; Sharabi, Kfir; Sohn, Jee Hyung; Yuan, Bo; Latorre-Muro, Pedro; Qin, Xin; Yook, Jin-Seon; Lin, Hua; Yu, Deyang; Camporez, João Paulo G; Kajimura, Shingo; Shulman, Gerald I; Hui, Sheng; Kamenecka, Theodore M; Griffin, Patrick R; Puigserver, Pere
