日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Unraveling chemotherapy-evoked hepatic dysfunction: a deep dive into cyclophosphamide-related liver injury

揭示化疗引起的肝功能障碍：深入探讨环磷酰胺相关的肝损伤

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-025-04583-0
Sharata, Ehab E; Attya, Mina Ezzat; Khalaf, Marwa M; Rofaeil, Remon Roshdy; Hemeida, Ramadan A M; Abo-Youssef, Amira M
肝损伤
毒理研究
发表日期：2026
文献求助 收藏

Molecular mechanisms underlying cyclophosphamide-induced ovarian injury and protective strategies

环磷酰胺诱导卵巢损伤的分子机制及保护策略

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-025-04550-9
Sharata, Ehab E; Bakry, Taha; Atta, Habiba Gamal; Mohammed, Habiba Atef; Diab, Nazema Shaker; Atef, Rofaida Ashraf; Hosney, Roaa Sayed; Omar, Mahmoud Mohamed; Hemeida, Ramadan A M
发表日期：2026
文献求助 收藏

Apremilast ameliorates methotrexate-induced renal injury in rats: role of TLR4/NF-κB/P38 MAPK/caspase-3 and Nrf2/HO-1 signaling pathways.

阿普米司特可改善甲氨蝶呤诱导的大鼠肾损伤：TLR4/NF-κB/P38 MAPK/caspase-3 和 Nrf2/HO-1 信号通路的作用。

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-025-04846-w
Mohyeldin Reham H, Sharata Ehab E, Abdelnaser Mahmoud, Attya Mina Ezzat, Kotb Al Shaimaa Mahmoud, Rofaeil Remon Roshdy
肾损伤
信号转导
TLR4
Mapk
ASPA
NRF2
p38 MAPK
发表日期：2026
文献求助 收藏

Buspirone combats cyclophosphamide-provoked hepatotoxicity in rats via activation of AMPK/Nrf2/HO-1 and suppression of NF-κB p65 /NLRP3 inflammasome pathways.

丁螺环酮通过激活 AMPK/Nrf2/HO-1 和抑制 NF-κB p65 /NLRP3 炎症小体通路来对抗环磷酰胺引起的大鼠肝毒性。

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-025-04718-3
Khalaf Marwa M, Sharata Ehab E, Khallaf Waleed A I, Attya Mina Ezzat, Abo-Youssef Amira M, Hemeida Ramadan A M, Rofaeil Remon Roshdy
炎症/感染
LRP3
NRF2
NLRP3
炎性小体
AMPK
炎性小体
发表日期：2026
文献求助 收藏

Memantine abrogates testicular dysfunction induced by risperidone in rats with a potential role of ERK1/2-Nrf2-caspase-3 signaling pathway.

美金刚可消除利培酮引起的大鼠睾丸功能障碍，这可能与 ERK1/2-Nrf2-caspase-3 信号通路有关

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-94760-1
Mohyeldin Reham H, Sharata Ehab E, Fawzy Michael Atef, Attya Mina Ezzat, Welson Nermeen N, Rofaeil Remon Roshdy
信号转导
发表日期：2025
文献求助 收藏

Modulating platelet-activating factor by rupatadine attenuates gentamicin-induced nephrotoxicity in rats via NF-κB/caspase-3 and Nrf2/HO-1 signaling cascades

卢帕他定通过NF-κB/caspase-3和Nrf2/HO-1信号级联调节血小板活化因子，从而减轻庆大霉素诱导的大鼠肾毒性。

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-025-04327-0
Mohyeldin, Reham H; Abdelnaser, Mahmoud; Sharata, Ehab E; Kotb, Al Shaimaa Mahmoud; Ali, Fatma F; Attya, Mina Ezzat; Tawfik, Heba M; Elrehany, Mahmoud A; Rofaeil, Remon Roshdy
血小板
信号转导
NF-κB
Rat
毒理研究
发表日期：2025
文献求助 收藏

Tumor differentiation impacts response to neoadjuvant therapy and survival in patients with esophageal adenocarcinoma

肿瘤分化程度会影响食管腺癌患者对新辅助治疗的反应和生存期。

期刊:Journal of Thoracic and Cardiovascular Surgery
影响因子:4.4
doi:10.1016/j.jtcvs.2023.09.055
McKay, Sarah C; Louie, Brian E; Molena, Daniela; Andrews, Weston G; Boerner, Thomas; Hofstetter, Wayne L; Yeung, Jonathan; Darling, Gail E; Sharata, Ahmed; Peyre, Christian G; Dunn, Colin; Lipham, John C; Marginean, Horia; DeMeester, Steven R
肿瘤
肿瘤免疫
发表日期：2024
文献求助 收藏

Vincamine exerts hepato-protective activity during colon ligation puncture-induced sepsis by modulating oxidative stress, apoptosis, and TNFα/Nrf-2/Keap-1 signaling pathways

长春胺通过调节氧化应激、细胞凋亡和 TNFα/Nrf-2/Keap-1 信号通路在结肠结扎穿刺诱发的脓毒症中发挥保肝作用

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-69729-1
Rania Alaaeldin #, Reham H Mohyeldin #, Ehab E Sharata, Mina Ezzat Attya, Moustafa Fathy
免疫
细胞生物学
其它细胞
Apoptosis
发表日期：2024
文献求助 收藏

The protective effect of vinpocetine against Estradiol-benzoate induced cervical hyperkeratosis in female rats via modulation of SIRT1/Nrf2, and NLRP3 inflammasome

长春西汀通过调节 SIRT1/Nrf2 和 NLRP3 炎症小体对雌二醇苯甲酸酯诱导的雌性大鼠宫颈角化过度具有保护作用

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-69431-2
Remon R Rofaeil, Reham H Mohyeldin, Ehab E Sharata, Mina Ezzat Attya, Hany Essawy, Osama A Ibrahim, Walaa Yehia Abdelzaher
免疫
炎性小体
发表日期：2024
文献求助 收藏

A Novel Technique for Inguinal Hernia Repair in Patients With Nonmalignant Ascites

一种治疗非恶性腹水患者腹股沟疝的新技术

期刊:Cureus Journal of Medical Science
影响因子:1.3
doi:10.7759/cureus.75401
Dalby, Claire; Brenner, Sinead L; Sharata, Ahmed M; Winder, Nicolette M; Kuo, Paul C
发表日期：2024
文献求助 收藏