日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity

IFN-γ 可对人呼吸道巨噬细胞进行代谢重编程,从而导致糖酵解依赖性功能可塑性。

Donal J Cox ,Sarah A Connolly ,Cilian Ó Maoldomhnaigh ,Aenea A I Brugman ,Olivia Sandby Thomas ,Emily Duffin ,Karl M Gogan ,Oisin Ó Gallchobhair ,Dearbhla M Murphy ,Sinead A O'Rourke ,Finbarr O'Connell ,Parthiban Nadarajan ,James J Phelan ,Laura E Gleeson ,Sharee A Basdeo # ,Joseph Keane #

Human Macrophages Activate Bystander Neutrophils' Metabolism and Effector Functions When Challenged with Mycobacterium tuberculosis

人类巨噬细胞在受到结核分枝杆菌攻击时激活旁观者中性粒细胞的代谢和效应功能

Dearbhla M Murphy, Anastasija Walsh, Laura Stein, Andreea Petrasca, Donal J Cox, Kevin Brown, Emily Duffin, Gráinne Jameson, Sarah A Connolly, Fiona O'Connell, Jacintha O'Sullivan, Sharee A Basdeo, Joseph Keane, James J Phelan

Trained immunity is induced in humans after immunization with an adenoviral vector COVID-19 vaccine

接种腺病毒载体新冠疫苗后,人体可产生训练免疫力。

Dearbhla M Murphy ,Donal J Cox ,Sarah A Connolly ,Eamon P Breen ,Aenea Ai Brugman ,James J Phelan ,Joseph Keane ,Sharee A Basdeo

The Warburg Effect Occurs Rapidly in Stimulated Human Adult but Not Umbilical Cord Blood Derived Macrophages

瓦伯格效应在受刺激的成人中迅速发生,但在脐带血来源的巨噬细胞中则不会发生

Cilian Ó Maoldomhnaigh, Donal J Cox, James J Phelan, Fergal D Malone, Joseph Keane, Sharee A Basdeo

Lactate Alters Metabolism in Human Macrophages and Improves Their Ability to Kill Mycobacterium tuberculosis

乳酸改变人体巨噬细胞的代谢并提高其杀死结核分枝杆菌的能力

Cilian Ó Maoldomhnaigh, Donal J Cox, James J Phelan, Morgane Mitermite, Dearbhla M Murphy, Gina Leisching, Lorraine Thong, Seónadh M O'Leary, Karl M Gogan, Kate McQuaid, Amy M Coleman, Stephen V Gordon, Sharee A Basdeo, Joseph Keane

The Effect of Tuberculosis Antimicrobials on the Immunometabolic Profiles of Primary Human Macrophages Stimulated with Mycobacterium tuberculosis

结核病抗菌药物对结核分枝杆菌刺激的原代人巨噬细胞免疫代谢特征的影响

Christina Cahill, Dónal J Cox, Fiona O'Connell, Sharee A Basdeo, Karl M Gogan, Cilian Ó'Maoldomhnaigh, Jacintha O'Sullivan, Joseph Keane, James J Phelan

The Iron Chelator Desferrioxamine Increases the Efficacy of Bedaquiline in Primary Human Macrophages Infected with BCG

铁螯合剂去铁胺可增强贝达喹啉对感染 BCG 的原代人类巨噬细胞的疗效

Christina Cahill, Fiona O'Connell, Karl M Gogan, Donal J Cox, Sharee A Basdeo, Jacintha O'Sullivan, Stephen V Gordon, Joseph Keane, James J Phelan

Inhibiting Histone Deacetylases in Human Macrophages Promotes Glycolysis, IL-1β, and T Helper Cell Responses to Mycobacterium tuberculosis

抑制人类巨噬细胞中的组蛋白去乙酰化酶可促进糖酵解、IL-1β 和 T 辅助细胞对结核分枝杆菌的反应

Donal J Cox, Amy M Coleman, Karl M Gogan, James J Phelan, Cilian Ó Maoldomhnaigh, Pádraic J Dunne, Sharee A Basdeo, Joseph Keane

IL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cells

IL-27 通过抑制 Th17 细胞介导多发性硬化症患者对 IFN-β 治疗的反应

Cheryl M Sweeney, Roisin Lonergan, Sharee A Basdeo, Katie Kinsella, Lara S Dungan, Sarah C Higgins, Patrick J Kelly, Lisa Costelloe, Niall Tubridy, Kingston H G Mills, Jean M Fletcher