日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Determining P-glycoprotein-drug interactions: evaluation of reconstituted P-glycoprotein in a liposomal system and LLC-MDR1 polarized cell monolayers

确定 P-糖蛋白-药物相互作用:在脂质体系统和 LLC-MDR1 极化细胞单层中评估重组 P-糖蛋白

Melchior, Donald L; Sharom, Frances J; Evers, Raymond; Wright, George E; Chu, Joseph W K; Wright, Stephen E; Chu, Xiaoyan; Yabut, Jocelyn

The reconstituted Escherichia coli MsbA protein displays lipid flippase activity

重组的大肠杆菌MsbA蛋白显示出脂质翻转酶活性

Eckford, Paul D W; Sharom, Frances J

The ABC transporter MsbA interacts with lipid A and amphipathic drugs at different sites

ABC转运蛋白MsbA与脂质A和两亲性药物在不同位点相互作用。

Siarheyeva, Alena; Sharom, Frances J

Rapid regulation of protein activity in fission yeast

裂殖酵母中蛋白质活性的快速调控

Bøe, Cathrine A; Garcia, Ignacio; Pai, Chen-Chun; Sharom, Jeffrey R; Skjølberg, Henriette C; Boye, Erik; Kearsey, Stephen; Macneill, Stuart A; Tyers, Michael D; Grallert, Beáta

Confinement of caspase-12 proteolytic activity to autoprocessing

caspase-12 蛋白水解活性被限制在自我加工阶段

Sophie Roy, Jeffrey R Sharom, Caroline Houde, Thomas P Loisel, John P Vaillancourt, Wei Shao, Maya Saleh, Donald W Nicholson

Conformational and functional characterization of trapped complexes of the P-glycoprotein multidrug transporter

P-糖蛋白多药转运体捕获复合物的构象和功能表征

Russell, Paula L; Sharom, Frances J

Combined chemical and enzymatic stable isotope labeling for quantitative profiling of detergent-insoluble membrane proteins isolated using Triton X-100 and Brij-96

结合化学和酶法稳定同位素标记,对使用 Triton X-100 和 Brij-96 分离的去垢剂不溶性膜蛋白进行定量分析

Blonder, Josip; Yu, Li-Rong; Radeva, Galina; Chan, King C; Lucas, David A; Waybright, Timothy J; Issaq, Haleem J; Sharom, Frances J; Veenstra, Timothy D

The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids

重组的P-糖蛋白多药转运体是一种葡萄糖基神经酰胺和其他简单糖鞘脂的翻转酶。

Eckford, Paul D W; Sharom, Frances J

A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size

动态转录网络将生长潜能传递给核糖体合成和临界细胞大小。

Jorgensen, Paul; Rupes, Ivan; Sharom, Jeffrey R; Schneper, Lisa; Broach, James R; Tyers, Mike

Linear and cyclic peptides as substrates and modulators of P-glycoprotein: peptide binding and effects on drug transport and accumulation

线性肽和环状肽作为P-糖蛋白的底物和调节剂:肽结合及其对药物转运和蓄积的影响

Sharom, F J; Lu, P; Liu, R; Yu, X