日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An organ-chip model of sporadic ALS using iPSC-derived spinal cord motor neurons and an integrated blood-brain-like barrier

利用诱导多能干细胞衍生的脊髓运动神经元和整合的血脑屏障构建散发性肌萎缩侧索硬化症的器官芯片模型

Deepti Lall ,Michael J Workman ,Samuel Sances ,Briana N Ondatje ,Shaughn Bell ,George Lawless ,Amanda Woodbury ,Dylan West ,Amanda Meyer ,Andrea Matlock ,Vineet Vaibhav ,Jennifer E Van Eyk ,Clive N Svendsen

Organ-Chips Enhance the Maturation of Human iPSC-Derived Dopamine Neurons

器官芯片促进人类 iPSC 衍生的多巴胺神经元的成熟

Maria G Otero, Shaughn Bell, Alexander H Laperle, George Lawless, Zachary Myers, Marian A Castro, Jaquelyn M Villalba, Clive N Svendsen

C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation

C9orf72 缺乏会促进衰老过程中小胶质细胞介导的突触丢失和淀粉样蛋白积累

Deepti Lall, Ileana Lorenzini, Thomas A Mota, Shaughn Bell, Thomas E Mahan, Jason D Ulrich, Hayk Davtyan, Jessica E Rexach, A K M Ghulam Muhammad, Oksana Shelest, Jesse Landeros, Michael Vazquez, Junwon Kim, Layla Ghaffari, Jacqueline Gire O'Rourke, Daniel H Geschwind, Mathew Blurton-Jones, David M

C9orf72 in myeloid cells suppresses STING-induced inflammation

髓系细胞中的C9orf72抑制STING诱导的炎症

Madelyn E McCauley ,Jacqueline Gire O'Rourke ,Alberto Yáñez ,Janet L Markman ,Ritchie Ho ,Xinchen Wang ,Shuang Chen ,Deepti Lall ,Mengyao Jin ,A K M G Muhammad ,Shaughn Bell ,Jesse Landeros ,Viviana Valencia ,Matthew Harms ,Moshe Arditi ,Caroline Jefferies ,Robert H Baloh

Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder

比较三种一致的患者特异性细胞类型,用于构建人类遗传性雪旺细胞疾病模型

Bipasha Mukherjee-Clavin ,Ruifa Mi ,Barbara Kern ,In Young Choi ,Hotae Lim ,Yohan Oh ,Benjamin Lannon ,Kevin J Kim ,Shaughn Bell ,Junho K Hur ,Woochang Hwang ,Young Hyun Che ,Omer Habib ,Robert H Baloh ,Kevin Eggan ,Gerald Brandacher ,Ahmet Hoke ,Lorenz Studer ,Yong Jun Kim ,Gabsang Lee

Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model

恢复线粒体融合蛋白平衡可预防夏科-马里-图斯病 2A 型模型中的轴突变性

Yueqin Zhou ,Sharon Carmona ,A K M G Muhammad ,Shaughn Bell ,Jesse Landeros ,Michael Vazquez ,Ritchie Ho ,Antonietta Franco ,Bin Lu ,Gerald W Dorn 2nd ,Shaomei Wang ,Cathleen M Lutz ,Robert H Baloh

Cell transplantation strategies for acquired and inherited disorders of peripheral myelin

获得性和遗传性外周髓鞘疾病的细胞移植策略

A K M G Muhammad, Kevin Kim, Irina Epifantseva, Arwin Aghamaleky-Sarvestany, Megan E Simpkinson, Sharon Carmona, Jesse Landeros, Shaughn Bell, John Svaren, Robert H Baloh

C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD

C9orf72 BAC 转基因小鼠表现出 ALS/FTD 的典型病理特征

Jacqueline G O'Rourke, Laurent Bogdanik, A K M G Muhammad, Tania F Gendron, Kevin J Kim, Andrew Austin, Janet Cady, Elaine Y Liu, Jonah Zarrow, Sharday Grant, Ritchie Ho, Shaughn Bell, Sharon Carmona, Megan Simpkinson, Deepti Lall, Kathryn Wu, Lillian Daughrity, Dennis W Dickson, Matthew B Harms, Le

Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones

热休克期间 TDP-43 的朊病毒样核聚集受 HSP40/70 分子伴侣调控

Maria Udan-Johns, Rocio Bengoechea, Shaughn Bell, Jieya Shao, Marc I Diamond, Heather L True, Conrad C Weihl, Robert H Baloh

Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion

靶向具有 C9ORF72 重复扩增的 ALS 患者 iPSC 衍生运动神经元中的 RNA 焦点

Dhruv Sareen, Jacqueline G O'Rourke, Pratap Meera, A K M G Muhammad, Sharday Grant, Megan Simpkinson, Shaughn Bell, Sharon Carmona, Loren Ornelas, Anais Sahabian, Tania Gendron, Leonard Petrucelli, Michael Baughn, John Ravits, Matthew B Harms, Frank Rigo, C Frank Bennett, Thomas S Otis, Clive N Sven