日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Modeling late-onset Alzheimer's disease neuropathology via direct neuronal reprogramming

通过直接神经元重编程模拟晚发性阿尔茨海默病神经病理学

Sun, Zhao; Kwon, Ji-Sun; Ren, Yudong; Chen, Shawei; Walker, Courtney K; Lu, Xinguo; Cates, Kitra; Karahan, Hande; Sviben, Sanja; Fitzpatrick, James A J; Valdez, Clarissa; Houlden, Henry; Karch, Celeste M; Bateman, Randall J; Sato, Chihiro; Mennerick, Steven J; Diamond, Marc I; Kim, Jungsu; Tanzi, Rudolph E; Holtzman, David M; Yoo, Andrew S

Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1-TFEB pathway to Huntington's disease neurodegeneration

人类神经元衰老的纵向模型揭示了 RCAN1-TFEB 通路对亨廷顿病神经变性的贡献

Seong Won Lee #, Young Mi Oh #, Matheus B Victor, Yan Yang, Shawei Chen, Ilya Strunilin, Sonika Dahiya, Roland E Dolle, Stephen C Pak, Gary A Silverman, David H Perlmutter, Andrew S Yoo

SAK3 confers neuroprotection in the neurodegeneration model of X-linked Dystonia-Parkinsonism

SAK3 在 X 连锁肌张力障碍-帕金森综合征的神经退行性模型中发挥神经保护作用。

Aryal, Shivani; Chen, Shawei; Burbach, Kyle F; Yang, Yan; Capano, Lucia S; Kim, Woo Kyung; Bragg, D Cristopher; Yoo, Andrew

Longitudinal modeling of human neuronal aging identifies RCAN1-TFEB pathway contributing to neurodegeneration of Huntington's disease

人类神经元老化的纵向模型确定了 RCAN1-TFEB 通路导致亨廷顿氏病的神经退行性病变

Seong Won Lee, Young Mi Oh, Matheus B Victor, Ilya Strunilin, Shawei Chen, Sonika Dahiya, Roland E Dolle, Stephen C Pak, Gary A Silverman, David H Perlmutter, Andrew S Yoo

Endogenous recapitulation of Alzheimer's disease neuropathology through human 3D direct neuronal reprogramming

通过人类3D直接神经元重编程实现阿尔茨海默病神经病理学的内源性重现

Sun, Zhao; Kwon, Ji-Sun; Ren, Yudong; Chen, Shawei; Cates, Kitra; Lu, Xinguo; Walker, Courtney K; Karahan, Hande; Sviben, Sanja; Fitzpatrick, James A J; Valdez, Clarissa; Houlden, Henry; Karch, Celeste M; Bateman, Randall J; Sato, Chihiro; Mennerick, Steven J; Diamond, Marc I; Kim, Jungsu; Tanzi, Rudolph E; Holtzman, David M; Yoo, Andrew S

Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy

直接重编程的患者来源纹状体神经元模拟的与年龄相关的亨廷顿氏病进展突出了自噬受损

Young Mi Oh #, Seong Won Lee #, Woo Kyung Kim, Shawei Chen, Victoria A Church, Kitra Cates, Tiandao Li, Bo Zhang, Roland E Dolle, Sonika Dahiya, Stephen C Pak, Gary A Silverman, David H Perlmutter, Andrew S Yoo

Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs

利用microRNA逐步解析人类成纤维细胞向神经元的命运转化

Kitra Cates ,Matthew J McCoy ,Ji-Sun Kwon ,Yangjian Liu ,Daniel G Abernathy ,Bo Zhang ,Shaopeng Liu ,Paul Gontarz ,Woo Kyung Kim ,Shawei Chen ,Wenjun Kong ,Joshua N Ho ,Kyle F Burbach ,Harrison W Gabel ,Samantha A Morris ,Andrew S Yoo

Methylprednisolone protects oligodendrocytes but not neurons after spinal cord injury

甲基强的松龙在脊髓损伤后保护少突胶质细胞但不保护神经元

Jin-Moo Lee, Ping Yan, Qingli Xiao, Shawei Chen, Kuang-Yung Lee, Chung Y Hsu, Jan Xu

Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway

β-淀粉样蛋白肽通过激活中性鞘磷脂酶-神经酰胺通路诱导少突胶质细胞死亡。

Lee, Jiunn-Tay; Xu, Jan; Lee, Jin-Moo; Ku, Grace; Han, Xianlin; Yang, Ding-I; Chen, Shawei; Hsu, Chung Y