日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Altered subgenomic RNA abundance provides unique insight into SARS-CoV-2 B.1.1.7/Alpha variant infections

亚基因组 RNA 丰度的改变为 SARS-CoV-2 B.1.1.7/Alpha 变异感染提供了独特的见解

Matthew D Parker, Hazel Stewart, Ola M Shehata, Benjamin B Lindsey, Dhruv R Shah, Sharon Hsu, Alexander J Keeley, David G Partridge, Shay Leary, Alison Cope, Amy State, Katie Johnson, Nasar Ali, Rasha Raghei, Joe Heffer, Nikki Smith, Peijun Zhang, Marta Gallis, Stavroula F Louka, Hailey R Hornsby, H

Abacavir inhibits but does not cause self-reactivity to HLA-B*57:01-restricted EBV specific T cell receptors

阿巴卡韦抑制但不会引起对 HLA-B*57:01 限制性 EBV 特异性 T 细胞受体的自身反应

Anuradha Sooda, Francois Rwandamuriye, Celestine N Wanjalla, Lichen Jing, David M Koelle, Bjoern Peters, Shay Leary, Abha Chopra, Michael A Calderwood, Simon A Mallal, Rebecca Pavlos, Mark Watson, Elizabeth J Phillips, Alec J Redwood

Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells

单细胞分析显示,同时患有 HIV 和糖尿病的患者的脂肪组织中富含克隆性、细胞毒性和 CMV 特异性 CD4+ T 细胞。

Celestine N Wanjalla ,Wyatt J McDonnell ,Ramesh Ram ,Abha Chopra ,Rama Gangula ,Shay Leary ,Mona Mashayekhi ,Joshua D Simmons ,Christian M Warren ,Samuel Bailin ,Curtis L Gabriel ,Liang Guo ,Briana D Furch ,Morgan C Lima ,Beverly O Woodward ,LaToya Hannah ,Mark A Pilkinton ,Daniela T Fuller ,Kenji Kawai ,Renu Virmani ,Aloke V Finn ,Alyssa H Hasty ,Simon A Mallal ,Spyros A Kalams ,John R Koethe

Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data

SARS-CoV-2基因组测序数据中的亚基因组RNA鉴定

Matthew D Parker # ,Benjamin B Lindsey # ,Shay Leary ,Silvana Gaudieri ,Abha Chopra ,Matthew Wyles ,Adrienn Angyal ,Luke R Green ,Paul Parsons ,Rachel M Tucker ,Rebecca Brown ,Danielle Groves ,Katie Johnson ,Laura Carrilero ,Joe Heffer ,David G Partridge ,Cariad Evans ,Mohammad Raza ,Alexander J Keeley ,Nikki Smith ,Ana Da Silva Filipe ,James G Shepherd ,Chris Davis ,Sahan Bennett ,Vattipally B Sreenu ,Alain Kohl ,Elihu Aranday-Cortes ,Lily Tong ,Jenna Nichols ,Emma C Thomson ,Simon Mallal ,Thushan I de Silva

In chronic infection, HIV gag-specific CD4+ T cell receptor diversity is higher than CD8+ T cell receptor diversity and is associated with less HIV quasispecies diversity

在慢性感染中,HIV gag 特异性 CD4+ T 细胞受体多样性高于 CD8+ T 细胞受体多样性,且与 HIV 准物种多样性较低相关

Mark A Pilkinton, Wyatt J McDonnell, Louise Barnett, Abha Chopra, Rama Gangula, Katie D White, Shay Leary, Jennifer Currenti, Silvana Gaudieri, Simon A Mallal, Spyros A Kalams

Repair of an Attenuated Low-Passage Murine Cytomegalovirus Bacterial Artificial Chromosome Identifies a Novel Spliced Gene Essential for Salivary Gland Tropism

修复减毒低代小鼠巨细胞病毒细菌人工染色体,鉴定出一种对唾液腺趋向性至关重要的新型剪接基因

Alec James Redwood,Laura Lee Masters,Baca Chan,Shay Leary,Cathy Forbes,Stipan Jonjić,Vanda Juranić Lisnić,Berislav Lisnić #,Lee Martin Smith #

Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV

对HIV垂直传播后适应性的深度序列分析揭示了免疫压力对HIV进化的影响

Jennifer Currenti,Abha Chopra,Mina John,Shay Leary,Elizabeth McKinnon,Eric Alves,Mark Pilkinton,Rita Smith,Louise Barnett,Wyatt J McDonnell,Michaela Lucas,Francine Noel,Simon Mallal,Joseph A Conrad,Spyros A Kalams,Silvana Gaudieri

Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma

鉴定恶性间皮瘤中针对预测新抗原的 CD8+ T 细胞反应

Sophie Sneddon, Craig M Rive, Shaokang Ma, Ian M Dick, Richard J N Allcock, Scott D Brown, Robert A Holt, Mark Watson, Shay Leary, Y C Gary Lee, Bruce W S Robinson, Jenette Creaney

Pan-genomic analyses identify key Helicobacter pylori pathogenic loci modified by carcinogenic host microenvironments

泛基因组分析确定了致癌宿主微环境修饰的关键幽门螺杆菌致病位点

Jennifer M Noto, Abha Chopra, John T Loh, Judith Romero-Gallo, M Blanca Piazuelo, Mark Watson, Shay Leary, Amber C Beckett, Keith T Wilson, Timothy L Cover, Simon Mallal, Dawn A Israel, Richard M Peek

HIV integration sites in latently infected cell lines: evidence of ongoing replication

潜在感染细胞系中的 HIV 整合位点:持续复制的证据

Jori Symons, Abha Chopra, Eva Malatinkova, Ward De Spiegelaere, Shay Leary, Don Cooper, Chike O Abana, Ajantha Rhodes, Simin D Rezaei, Linos Vandekerckhove, Simon Mallal, Sharon R Lewin, Paul U Cameron