Microglia-derived APOE2 improves remyelination even in the presence of endogenous APOE4.
即使在存在内源性 APOE4 的情况下,小胶质细胞衍生的 APOE2 也能改善髓鞘再生。
期刊:Journal of Neuroinflammation
影响因子:10.1
doi:10.1186/s12974-025-03639-5
Nolt Georgia L, Golden Lesley R, Thorpe Shealee P, Funnell Jessica L, Stephens Isaiah O, Hernandez Gabriela, MacLean Steven M, Lucido Chloe C, Brock Chesney R, Pallerla Akhil V, Adreon Darcy R, Williams Holden C, Morganti Josh M, Johnson Lance A