日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

T cell exhaustion in poorly immunogenic HCC is partially rescued by checkpoint blockade but suppressed by oncolytic virotherapy

在免疫原性较差的肝细胞癌中,T细胞耗竭可通过免疫检查点阻断部分挽救,但可通过溶瘤病毒疗法抑制。

Thanich Sangsuwannukul ,Benjamin Kendall ,Jason Tonne ,Olivia Liseth ,Jill Thompson ,Kamonlapat Supimon ,Muriel M Metko ,Alex Chen ,Maria P Chiriboga Yerovi ,Rosa Maria Diaz ,Laura Evgin ,Mason J Webb ,Jacob van Vloten ,Satdarshan P Monga ,Sheeba Irshad ,Mark McNiven ,Lewis Roberts ,Richard G Vile

Exploiting viral infection/vaccination to focus high-affinity T cell populations into tumors using oncolytic viro-immunotherapy

利用病毒感染/疫苗接种,通过溶瘤病毒免疫疗法将高亲和力T细胞群定向输送到肿瘤部位。

Alexa Veliz Rios,Muriel Metko,Jason Tonne,Jill Thompson,Benjamin Kendall,Alex Chen,Haley Mudrick,David Masopust,Sheeba Irshad,Mary Barry,Michael A Barry,Rosa Maria Diaz,Richard Vile

Anti-EGFR Antibody-Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth

携带靶向 CDK 抑制剂的抗 EGFR 抗体药物偶联物可限制三阴性乳腺癌的生长

Anthony Cheung, Alicia M Chenoweth, Annelie Johansson, Roman Laddach, Naomi Guppy, Jennifer Trendell, Benjamina Esapa, Antranik Mavousian, Blanca Navarro-Llinas, Syed Haider, Pablo Romero-Clavijo, Ricarda M Hoffmann, Paolo Andriollo, Khondaker M Rahman, Paul Jackson, Sophia Tsoka, Sheeba Irshad, Ioa

Cancer Immunotherapy Using AIRE Conditioning of the Tumor Epitopeome

利用 AIRE 调节肿瘤表位进行癌症免疫治疗

Richard Vile, Jose Pulido, Alex Chen, Benjamin Kendall, Jason Tonne, Muriel Metko, Jill Thompson, Thanich Sangsuwannukul, Maria Chiriboga Yerovi, Rosa Diaz, Mason Webb, Amanda Huff, Madelyn Moore, Matthew Schuelke, Sheeba Irshad, Elizabeth Appleton, Alan Melcher

Serum-derived extracellular vesicles from breast cancer patients contribute to differential regulation of T-cell-mediated immune-escape mechanisms in breast cancer subtypes

乳腺癌患者血清来源的细胞外囊泡有助于乳腺癌亚型中 T 细胞介导的免疫逃逸机制的差异调节

Rosalind Graham, Patrycja Gazinska, Birong Zhang, Atousa Khiabany, Shubhankar Sinha, Thanussuyah Alaguthurai, Fabian Flores-Borja, Jose Vicencio, Fabienne Beuron, Ioannis Roxanis, Rafal Matkowski, Revadee Liam-Or, Andrew Tutt, Tony Ng, Khuloud T Al-Jamal, You Zhou, Sheeba Irshad

Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy-Resistant Early Breast Cancers

新辅助化疗后高转移风险早期乳腺癌中NK细胞、中性粒细胞和B细胞免疫表型的动态变化

Patrycja Gazinska # ,Charlotte Milton # ,Jacopo Iacovacci ,Joseph Ward ,Richard Buus ,Thanussuyah Alaguthurai ,Rosalind Graham ,Ayse Akarca ,Esther Lips ,Kalnisha Naidoo ,Jelle Wesseling ,Teresa Marafioti ,Maggie Cheang ,Cheryl Gillett ,Yin Wu ,Aadil Khan ,Alan Melcher ,Roberto Salgado ,Mitch Dowsett ,Andrew Tutt ,Ioannis Roxanis ,Syed Haider ,Sheeba Irshad

Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients

严重急性呼吸综合征冠状病毒2感染癌症患者的急性免疫特征及其遗留影响

Sultan Abdul-Jawad ,Luca Baù ,Thanussuyah Alaguthurai ,Irene Del Molino Del Barrio ,Adam G Laing ,Thomas S Hayday ,Leticia Monin ,Miguel Muñoz-Ruiz ,Louisa McDonald ,Isaac Francos Quijorna ,Duncan McKenzie ,Richard Davis ,Anna Lorenc ,Julie Nuo En Chan ,Sarah Ryan ,Eva Bugallo-Blanco ,Rozalyn Yorke ,Shraddha Kamdar ,Matthew Fish ,Iva Zlatareva ,Pierre Vantourout ,Aislinn Jennings ,Sarah Gee ,Katie Doores ,Katharine Bailey ,Sophie Hazell ,Julien De Naurois ,Charlotte Moss ,Beth Russell ,Aadil A Khan ,Mark Rowley ,Reuben Benjamin ,Deborah Enting ,Doraid Alrifai ,Yin Wu ,You Zhou ,Paul Barber ,Tony Ng ,James Spicer ,Mieke Van Hemelrijck ,Mayur Kumar ,Jennifer Vidler ,Yadanar Lwin ,Paul Fields ,Sophia N Karagiannis ,Anthony C C Coolen ,Anne Rigg ,Sophie Papa ,Adrian C Hayday ,Piers E M Patten ,Sheeba Irshad