日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

What's on the menu?: metabolic constraints in the pancreatic tumor microenvironment

菜单上有什么?:胰腺肿瘤微环境中的代谢限制

Sheehan, Colin; Muir, Alexander

Tissue-specific tolerance mechanisms and lymph node co-drainage converge to shape T cell immunity in the upper digestive system and regulate pancreatic cancer progression

组织特异性耐受机制和淋巴结共同引流共同塑造上消化道的T细胞免疫,并调控胰腺癌的进展。

Zhou, Yixuan D; Wang, Peter; Schaffer, Emily; Komnick, Macy R; Brown, Hailey; Taylor, Gwen M; Fiske, Kay L; Sheehan, Colin; Dermody, Terence S; Muir, Alexander; Esterházy, Daria

Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer.

肿瘤营养压力会导致胰腺癌细胞产生耐药状态。

Sheehan Colin, Hu Lyndon, Cognet Guillaume, Croley Grace, Nguyen Thao Trang, Thomas-Toth Anika, Agovino Darby, Jonker Patrick B, Sadullozoda Mumina, Ziolkowski Leah M, Martin James K, Beutel Alica K, Dano Ranya, Khan Mohammed A, Halbrook Christopher J, Macleod Kay F, Weber Christopher R, LaBelle James L, Muir Alexander

Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis.

微环境中的精氨酸限制通过抑制脂质合成,使胰腺癌对多不饱和脂肪酸更加敏感

Jonker Patrick B, Sadullozoda Mumina, Cognet Guillaume, Saab Juan J Apiz, Sokol Kelly H, Wu Violet X, Kumari Deepa, Sheehan Colin, Ozgurses Mete E, Agovino Darby, Croley Grace, Patel Smit A, Bock-Hughes Althea, Macleod Kay F, Shah Hardik, Coloff Jonathan L, Lien Evan C, Muir Alexander

The requirement for mitochondrial respiration in cancer varies with disease stage

癌症对线粒体呼吸的需求随疾病阶段而异

Sheehan, Colin; Muir, Alexander

Tumor-derived extracellular vesicles: molecular parcels that enable regulation of the immune response in cancer

肿瘤来源的细胞外囊泡:调控癌症免疫反应的分子载体

Sheehan, Colin; D'Souza-Schorey, Crislyn