The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning.
化疗药物 CX-5461 的主要细胞毒性机制是拓扑异构酶 II 中毒
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1921649117
Bruno Peter M, Lu Mengrou, Dennis Kady A, Inam Haider, Moore Connor J, Sheehe John, Elledge Stephen J, Hemann Michael T, Pritchard Justin R