Shen Lei相关文献与解析，生知库 | 链接生命科学的每一步

Niu, Quanhao; Yan, Bei; Shen, Lei; Lin, Hao; Zhang, Xi; Wan, Zhenyu; Xu, Mutian; Zhang, Hui; Luo, Jie; Zhang, Lei; Shum, Perry Ping; Gao, Zhen; Wang, Jian

发表日期：2026

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TDRD3, a Tudor domain-containing protein, regulates Klf2-dependent T(reg) differentiation and function to modulate immune tolerance

TDRD3是一种含有Tudor结构域的蛋白质，它调节Klf2依赖的T(reg)细胞分化和功能，从而调节免疫耐受。

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.aea3960

Shi, Yun; Tao, Xiaoqun; Shen, Lei; Yuan, Yate-Ching; Wang, Guanpeng; Eurmsirilerd, Ethan; Chang, Rendell; Jia, Zhenyu; Shang, Weirong; Yang, Yanzhong; Sun, Zuoming

Epigenome editing based treatment: Progresses and challenges

基于表观基因组编辑的治疗：进展与挑战

期刊:Molecular Therapy

影响因子:12

doi:10.1016/j.ymthe.2025.08.047

Yuan, Luowei; Xiong, Yikai; Zhang, Yiming; Gu, Shen; Lei, Yong

表观遗传

发表日期：2026

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Polyethylene terephthalate microplastics exposure enhances the risk of ulcerative colitis: insights from multiomics integration, machine learning, and molecular docking reveal intestinal toxicity mechanisms

聚对苯二甲酸乙二醇酯微塑料暴露会增加溃疡性结肠炎的风险：多组学整合、机器学习和分子对接揭示了其肠道毒性机制

期刊:International Journal of Surgery

影响因子:10.1

doi:10.1097/JS9.0000000000003476

Yang, Xueli; Yan, Bo; Zhao, Yu; Zhou, Linxiang; Liu, Miao; Chen, Gong; Shen, Lei; Deng, Tao

Efficacy and Safety of Standardized Ethanol Extract of Purple Perilla (Perilla frutescens Britton var. acuta Kudo) Leaves in Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

紫苏（Perilla frutescens Britton var. acuta Kudo）叶标准化乙醇提取物对认知障碍的疗效和安全性：一项随机、双盲、安慰剂对照临床试验

期刊:Nutrients

影响因子:5

doi:10.3390/nu18060960

Baek, Hyang-Im; Joo, Jong Cheon; Kim, Sung-Kyu; Park, Mi-Houn; Cho, Gun Hee; Shen, Lei; Park, Soo Jung

神经科学

发表日期：2026

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Gut microbiota-derived cholic acid ameliorates lung inflammation in bronchopulmonary dysplasia through modulation of macrophage function.

肠道菌群衍生的胆酸通过调节巨噬细胞功能来改善支气管肺发育不良中的肺部炎症。

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2026.115398

Zhao Dongying, Gao Caixia, Zhu Danying, Zheng Xiaoyan, Sun Jiping, Liu Chengbo, Chen Lei, Shen Lei, Wang Xingyun, Zhang Yongjun

细胞生物学

巨噬细胞

Immunology/Inflammation

Effects of emotional motivation and cognitive control on prospective memory aftereffects of completed intention

情绪动机和认知控制对已完成意图的前瞻性记忆后效的影响

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-026-38675-5

Duan, Yajie; Shen, Lei; Liu, Wei; Chen, Ning

神经科学

发表日期：2026

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Targeted deletion of c-kit in TECs attenuates UUO-induced renal fibrosis through NF-κB pathway inhibition

靶向敲除肾小管上皮细胞中的c-kit基因可通过抑制NF-κB通路减轻UUO诱导的肾纤维化

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-026-42540-w

Xing, Zenghui; Wang, Hongfeng; Zhou, Yaguang; Chen, Shengxin; Han, Bing; Zhang, Yixuan; Zheng, Shengchun; Chen, Yan; Cai, Guangyan; Shen, Lei; Chen, Xiangmei; Sun, Xuefeng

Risk Prediction for Delayed Bleeding After Endoscopic Submucosal Dissection in Colorectal Precancerous Lesions Using Artificial Intelligence: Retrospective Clinical Trial

利用人工智能预测结直肠癌前病变内镜黏膜下剥离术后延迟出血的风险：回顾性临床试验

期刊:Diseases of the Colon & Rectum

影响因子:3.7

doi:10.1097/DCR.0000000000004095

Wu, Zunan; Yuan, Lei; Zhang, Shengjie; Cai, Chengfei; Yuan, Jingping; Liu, Yi; Tong, Qiaoyun; Zhang, Heng; Xia, Yutong; Wang, Hongyi; Xu, Xinrui; Li, Linfei; Shen, Lei; Ji, Mengyao

Obesity disrupts ILC2 metabolic and functional homeostasis by inhibiting mTORC1 signaling.

肥胖通过抑制 mTORC1 信号传导来破坏 ILC2 的代谢和功能稳态。

Publisher Correction: Realization of a Dirac-vortex topological photonic crystal fiber

出版商更正：狄拉克涡旋拓扑光子晶体光纤的实现

TDRD3, a Tudor domain-containing protein, regulates Klf2-dependent T(reg) differentiation and function to modulate immune tolerance

TDRD3是一种含有Tudor结构域的蛋白质，它调节Klf2依赖的T(reg)细胞分化和功能，从而调节免疫耐受。

Epigenome editing based treatment: Progresses and challenges

基于表观基因组编辑的治疗：进展与挑战

Polyethylene terephthalate microplastics exposure enhances the risk of ulcerative colitis: insights from multiomics integration, machine learning, and molecular docking reveal intestinal toxicity mechanisms

聚对苯二甲酸乙二醇酯微塑料暴露会增加溃疡性结肠炎的风险：多组学整合、机器学习和分子对接揭示了其肠道毒性机制

Efficacy and Safety of Standardized Ethanol Extract of Purple Perilla (Perilla frutescens Britton var. acuta Kudo) Leaves in Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

紫苏（Perilla frutescens Britton var. acuta Kudo）叶标准化乙醇提取物对认知障碍的疗效和安全性：一项随机、双盲、安慰剂对照临床试验

Gut microbiota-derived cholic acid ameliorates lung inflammation in bronchopulmonary dysplasia through modulation of macrophage function.

肠道菌群衍生的胆酸通过调节巨噬细胞功能来改善支气管肺发育不良中的肺部炎症。

Effects of emotional motivation and cognitive control on prospective memory aftereffects of completed intention

情绪动机和认知控制对已完成意图的前瞻性记忆后效的影响

Targeted deletion of c-kit in TECs attenuates UUO-induced renal fibrosis through NF-κB pathway inhibition

靶向敲除肾小管上皮细胞中的c-kit基因可通过抑制NF-κB通路减轻UUO诱导的肾纤维化

Risk Prediction for Delayed Bleeding After Endoscopic Submucosal Dissection in Colorectal Precancerous Lesions Using Artificial Intelligence: Retrospective Clinical Trial

利用人工智能预测结直肠癌前病变内镜黏膜下剥离术后延迟出血的风险：回顾性临床试验