Shen Qian相关文献与解析，生知库 | 链接生命科学的每一步

Fang Yan, Shen Qian, Lin Yao, Zhu Jing, Zhu Xiaolan, Huang Rui, Wu Yijia, Shen Feiyang, Li Qian, Zheng Guopei, Zhang Zhe, Chu Qian, Hu Junhao, Shen Jianfeng

PARP

LIN28B

LIN28

发表日期：2026

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A novel photosensitizer berberine derivative B12 induces apoptosis and suppresses HIF-1α expression in colorectal cancer cells via mitochondria-to-nucleus sequential-targeting

一种新型光敏剂小檗碱衍生物B12通过线粒体到细胞核的顺序靶向作用诱导结直肠癌细胞凋亡并抑制HIF-1α表达。

期刊:Acta Pharmacologica Sinica

影响因子:8.4

doi:10.1038/s41401-025-01728-y

Pei, Wen-Bin; Lei, Zi-Yu; Xie, Fu-Quan; Chen, Peng; Su, Yong-Cheng; Qin, Yu-Shan; Li, Jiang-Quan; Shen, Qian-Wen; Ma, Miao-Miao; Gao, Chun-Yi; Zhu, Jia-Chen; Xu, Ya-Jie; Zhang, Kai-Yue; Zhang, Wen-Qing; Zhang, Yan-Dong; Hu, Tian-Hui; Xu, Bei-Bei

Decoding mitochondrial signaling: neutrophil-tumor cell crosstalk in orchestrating cancer progression

解码线粒体信号传导：中性粒细胞-肿瘤细胞相互作用在调控癌症进展中的作用

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-025-07659-w

Shen, Qian; Pan, Xue; Li, Junchen; Li, Yi; Lin, Jin; Liu, Fudong; Jiang, Xiaochen; Zhang, Chuanlong; Pang, Bo

Novel Dual Strategy Based on EPR/AT for Optimizing Therapeutic Effect by Improving Drug Delivery System Physicochemical Properties and Regulating TME

基于EPR/AT的新型双策略，通过改善药物递送系统的理化性质和调控肿瘤微环境来优化治疗效果。

期刊:International Journal of Nanomedicine

影响因子:6.5

doi:10.2147/IJN.S559763

Chen, Long; Deng, Xiang; Shen, Qian; Chen, Min; Li, Churong; Wang, Shunxi

Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice

嗜性转变的AAV-PHP.eB介导的bFGF基因疗法可促进小鼠缺血性卒中后的多种神经修复

期刊:Neural Regeneration Research

影响因子:5.9

doi:10.4103/NRR.NRR-D-23-01802

Rubing Shi ，Jing Ye ，Ze Liu ，Cheng Wang ，Shengju Wu ，Hui Shen ，Qian Suo ，Wanlu Li ，Xiaosong He ，Zhijun Zhang ，Yaohui Tang ，Guo-Yuan Yang ，Yongting Wang

神经科学

发表日期：2026

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Comparison of postprocedural adverse events between same-day and separate-day combined EUS-guided fine-needle aspiration/biopsy and endoscopic retrograde cholangiopancreatography in patients with pancreatic mass and biliary obstruction: A retrospective cohort study

比较胰腺肿块合并胆道梗阻患者同日行与分日行超声内镜引导下细针穿刺/活检联合内镜逆行胰胆管造影术后不良事件：一项回顾性队列研究

期刊:Endoscopic Ultrasound

影响因子:5.4

doi:10.1097/eus.0000000000000174

Zou, Hong-Yuan; Li, Zheng-Dong; Zhu, Jia-Hui; Jin, Zhen-Dong; Liao, Zhuan; Li, Zhao-Shen; Qian, Yang-Yang; Wang, Lei

发表日期：2026

文献求助收藏

Novel AAV843 Vector-Mediated Gene Replacement Therapy Rescues Primary Hyperoxaluria Type I in Mice.

新型 AAV843 载体介导的基因替代疗法可挽救小鼠原发性高草酸尿症 I 型。

期刊:Cells

影响因子:5.2

doi:10.3390/cells15070629

Zhang Jingjia, Yin Ye, Ji Baowei, Sun Manqing, Jiang Yuanyan, Wu Xiaohui, Xiao Xiao, Shen Qian, Wu Xia, Xu Hong

发表日期：2026

文献求助收藏

Renal Tubule-Specific Deletion of Nephrocystin 3 (Nphp3) Causes Infantile Nephronophthisis-like Phenotypes in Mice.

肾小管特异性缺失肾囊蛋白 3 (Nphp3) 会导致小鼠出现类似婴儿肾痨的表型。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms27062687

Du Xuanjin, Wang Chunyan, Fang Ye, Wang Gangqi, Zhai Yihui, Shen Qian, Tang Xiaoshan, Xu Hong

发表日期：2026

文献求助收藏

Vitamin D Deficiency Activates Gdnf-Ret-pErk1/2 Signal and Induces Kidney Malformations in Mice.

维生素D缺乏激活Gdnf-Ret-pErk1/2信号通路并诱发小鼠肾脏畸形。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms27073042

Yu Minghui, Ye Ningli, Ju Haixin, Miao Qianfan, Wang Chunyan, Dai Rufeng, Chen Jing, Zhai Yihui, Sun Lei, Wu Xiaohui, Xu Hong, Shen Qian

Minnelide ameliorates Col4a5+/- mice by upregulating Col4a5 and alleviating endoplasmic reticulum stress.

Minnelide 通过上调 Col4a5 和缓解内质网应激来改善 Col4a5+/- 小鼠的状况。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2026.1761502

Ji Bao-Wei, Liu Jun-Chao, Wang Xue, Yin Ye, Zhang Jing-Jia, Wen Fu-Jie, Xu Hong, Shen Qian, Yu Jian

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites.

PARPi 结合纳米颗粒 LIN28B siRNA 用于治疗恶性腹水。

A novel photosensitizer berberine derivative B12 induces apoptosis and suppresses HIF-1α expression in colorectal cancer cells via mitochondria-to-nucleus sequential-targeting

一种新型光敏剂小檗碱衍生物B12通过线粒体到细胞核的顺序靶向作用诱导结直肠癌细胞凋亡并抑制HIF-1α表达。

Decoding mitochondrial signaling: neutrophil-tumor cell crosstalk in orchestrating cancer progression

解码线粒体信号传导：中性粒细胞-肿瘤细胞相互作用在调控癌症进展中的作用

Novel Dual Strategy Based on EPR/AT for Optimizing Therapeutic Effect by Improving Drug Delivery System Physicochemical Properties and Regulating TME

基于EPR/AT的新型双策略，通过改善药物递送系统的理化性质和调控肿瘤微环境来优化治疗效果。

Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice

嗜性转变的AAV-PHP.eB介导的bFGF基因疗法可促进小鼠缺血性卒中后的多种神经修复

Comparison of postprocedural adverse events between same-day and separate-day combined EUS-guided fine-needle aspiration/biopsy and endoscopic retrograde cholangiopancreatography in patients with pancreatic mass and biliary obstruction: A retrospective cohort study

比较胰腺肿块合并胆道梗阻患者同日行与分日行超声内镜引导下细针穿刺/活检联合内镜逆行胰胆管造影术后不良事件：一项回顾性队列研究

Novel AAV843 Vector-Mediated Gene Replacement Therapy Rescues Primary Hyperoxaluria Type I in Mice.

新型 AAV843 载体介导的基因替代疗法可挽救小鼠原发性高草酸尿症 I 型。

Renal Tubule-Specific Deletion of Nephrocystin 3 (Nphp3) Causes Infantile Nephronophthisis-like Phenotypes in Mice.

肾小管特异性缺失肾囊蛋白 3 (Nphp3) 会导致小鼠出现类似婴儿肾痨的表型。

Vitamin D Deficiency Activates Gdnf-Ret-pErk1/2 Signal and Induces Kidney Malformations in Mice.

维生素D缺乏激活Gdnf-Ret-pErk1/2信号通路并诱发小鼠肾脏畸形。

Minnelide ameliorates Col4a5+/- mice by upregulating Col4a5 and alleviating endoplasmic reticulum stress.

Minnelide 通过上调 Col4a5 和缓解内质网应激来改善 Col4a5+/- 小鼠的状况。