Defective RNA Polymerase III sensing of mitochondrial DNA in pulmonary epithelial cells impairs type I IFN immunity to SARS-CoV-2
肺上皮细胞中RNA聚合酶III对线粒体DNA的识别缺陷会损害针对SARS-CoV-2的I型干扰素免疫。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2522111123
Møhlenberg, Michelle; Jørgensen, Sofie Eg; Marije van der Sluis, Renée; Zillinger, Thomas; Hinke, Daniëla Maria; Hollensen, Anne Kruse; Hansen, Anne Louise; Hausfater, Pierre; Gorochov, Guy; Tubach, Florence; Ghosn, Jade; Laouenan, Cedric; Storgaard, Merete; Holm, Christian Kanstrup; Su, Helen; Pérez de Diego, Rebeca; Pujol, Aurora; Zhang, Shen-Ying; Zhang, Qian; Sales Luiz Vianna, Fernanda; Abel, Laurent; Cobat, Aurélie; Casanova, Jean-Laurent; Mogensen, Trine H
线粒体
免疫/内分泌
细胞生物学
上皮细胞
SARS-CoV-2