日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Camrelizumab plus CAPOX with camrelizumab based maintenance versus CAPOX alone as initial treatment for gastric or gastro-oesophageal junction adenocarcinoma: randomised phase 3 trial

卡瑞利珠单抗联合 CAPOX 方案（以卡瑞利珠单抗为基础的维持治疗）与单用 CAPOX 方案作为胃癌或胃食管交界处腺癌一线治疗的疗效比较：一项随机 3 期试验

期刊:Bmj-British Medical Journal
影响因子:42.7
doi:10.1136/bmj-2025-086115
Peng, Zhi; Zhang, Yanqiao; Xu, Huiting; Yang, Yan; Yang, Mudan; Zhang, Mingjun; Cheng, Ying; Chen, Xiaobing; Pan, Yueyin; Wang, Feng; Li, Qingshan; Xu, Nong; Liu, Likun; Gu, Kangsheng; Xiao, Juxiang; Zhang, Ruixing; Zhao, Qun; Chen, Jian; Lin, Lizhu; Chen, Yigui; Deng, Yanhong; Cai, Shirong; Bai, Bin; Wang, Yiru; Shen, Lin
胃癌
肿瘤
肿瘤免疫
发表日期：2026
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Spatial single-cell multi-omics characterization of the tumor microenvironment heterogeneity by HER-2 expression status in gastric cancer

基于HER-2表达状态的胃癌肿瘤微环境异质性的空间单细胞多组学表征

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-026-02577-x
Peng, Haoxin; Chen, Yang; Yao, Qian; Liang, Yueting; Chong, Xiaoyi; Luo, Yiming; Liu, Dan; Wang, Yakun; Li, Yanyan; Feng, Xujiao; Sun, Yu; Gong, Jifang; Peng, Zhi; Zhang, Xiaotian; Shen, Lin
胃癌
肿瘤
肿瘤免疫
细胞生物学
肿瘤微环境
单细胞
发表日期：2026
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SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts.

SPP1 通过刺激癌相关成纤维细胞中 CXCL12 的产生，驱动结直肠癌肝转移和免疫治疗耐药性。

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-24-4916
Liu Shengde, Zhang Zizhen, Wang Zhenghang, Liu Cheng, Liang Guanghao, Xu Ting, Li Zhiwei, Duan Xiaorui, Xu Gehan, Feng Xujiao, Feng Qin, Wang Qi, Han Dali, Zhang Cheng, Li Jian, Shen Lin
CXCL12
成纤维细胞
肿瘤
肠癌
肿瘤免疫
CXCL1
治疗耐药
细胞生物学
免疫/内分泌
发表日期：2026
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Ultrasensitive Diamond Cantilever-Based Optical Microphone

超灵敏金刚石悬臂式光学麦克风

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202516099
Tian, Shen; Lin, Chaonan; Qiao, Yingying; Feng, Mingyang; Gao, Yang; Mu, Kaijun; Jiao, Mingqi; Li, Lei; Shan, Chongxin
发表日期：2026
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Fecal microbiota transplantation combined with anti-PD-1 therapy in refractory microsatellite-stable gastric cancer: a phase I feasibility and safety study

粪便微生物移植联合抗PD-1疗法治疗难治性微卫星稳定型胃癌：一项I期可行性和安全性研究

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2025-013823
Zhang, Yifan; Xu, Xiaomin; Wang, Shulin; Yin, Xiaochen; Zhang, Bohan; Zhu, Zhengnong; Ji, Rujie; Zhu, Jing; He, Hermione; Cheng, Siyuan; Han, Zihan; Xie, Tong; Zhang, Xiaotian; Wang, Yakun; Shen, Si; Kou, Yan; Bao, Siyu; Liu, Yingyu; Cao, Baoran; Bonny, Christophe; Guo, Xiaohuan; Segal, Eran; Tan, Yan; Shen, Lin; Peng, Zhi
胃癌
肿瘤
肿瘤免疫
微生物学
PD-1
发表日期：2026
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Erdafitinib in Patients with FGFR-Altered Advanced or Metastatic Cholangiocarcinoma

Erdafitinib治疗FGFR改变的晚期或转移性胆管癌患者

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-2264
Pant, Shubham; Park, Joon Oh; Su, Wu-Chou; Loriot, Yohann; Carranza, Omar; Corassa, Marcelo; Doi, Toshihiko; Qin, Shukui; Tabernero, Josep; Prenen, Hans; Folprecht, Gunnar; Winter, Helen; Dal Molin, Graziela Z; Shen, Lin; Qian, Jiaqi; Liao, Huimin; Thomas, Shibu; Sweiti, Hussein; Triantos, Spyros; Feng, Yin-Hsun
肿瘤
胆管癌
肿瘤免疫
发表日期：2026
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Evaluating the efficacy and safety of an all-inside, all-suture meniscal repair device on arthroscopic meniscal repair: a prospective, multi-center, randomized controlled clinical trial

评估全内缝合式半月板修复装置在关节镜下半月板修复中的疗效和安全性：一项前瞻性、多中心、随机对照临床试验

期刊:International Journal of Surgery
影响因子:10.1
doi:10.1097/JS9.0000000000004608
Shen, Lin-Yi; Ge, Yunshen; Wu, Ziyin; Zhang, Shurong; Wan, Fang; Zheng, Xiaofei; Hou, Huige; Li, JieRuo; Wang, Jing; Zeng, Yuanjie; Jia, Zhen; Gao, Zhizeng; Chen, Wenzhao; Guo, Fengjin; Li, Hongyun; Chen, Shiyi
发表日期：2026
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Dynamic reprogramming of the tumor immune network via multicycle checkpoint degradation for cancer immunotherapy

通过多周期检查点降解动态重编程肿瘤免疫网络以进行癌症免疫治疗

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2525047123
Shi, Tao; Wu, Yuanyuan; Cai, Yiran; Luo, Yuting; Ren, Shiji; Cao, Yaning; Tang, Yin; Jiang, Zizheng; Hu, Shiyao; Xie, Wenxue; Chen, Yuanyuan; Shen, Lin; Xing, Hang; Wei, Jia
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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Impact of Helicobacter pylori infection on gut and intratumoral microbiome and its association with immunotherapy response in gastrointestinal cancer

幽门螺杆菌感染对肠道和肿瘤内微生物组的影响及其与胃肠道癌症免疫治疗反应的关系

期刊:BMC Medicine
影响因子:8.3
doi:10.1186/s12916-025-04575-0
Jia, Keren; Chen, Yang; Dai, Die; Xie, Yi; Peng, Haoxin; Cao, Yanshuo; Zou, Hua; Qiu, Chuangzhao; Tan, Yan; Zhang, Xiaotian; Lu, Zhihao; Yin, Xiaochen; Peng, Zhi; Li, Jian; Shen, Lin
肿瘤
肿瘤免疫
炎症/感染
微生物学
免疫/内分泌
发表日期：2026
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The clinical landscape of POLE-mutant colorectal cancer: a retrospective analysis of real-world outcome

POLE突变型结直肠癌的临床概况：真实世界结果的回顾性分析

期刊:BMC Medicine
影响因子:8.3
doi:10.1186/s12916-025-04611-z
Xu, Ting; Zhang, Xuhui; Wang, Zhenghang; Shen, Lin; Wang, Xicheng; Li, Jian
肿瘤
肠癌
肿瘤免疫
发表日期：2026
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