日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mammalian genome writing: Unlocking new length scales for genome engineering

哺乳动物基因组编写:解锁基因组工程的新尺度

Pinglay, Sudarshan; Atwater, John T; Brosh, Ran; Shendure, Jay; Maurano, Matthew T; Boeke, Jef D

Evolutionary transfer learning enables organism-wide inference of mammalian enhancer landscapes

进化迁移学习能够对哺乳动物增强子图谱进行全生物体范围的推断

Qiu, Chengxiang; Daza, Riza M; Welsh, Ian C; Patwardhan, Rupali P; Martin, Beth K; Li, Tony; Yang, Shizhao; Kempynck, Niklas; Taylor, Megan L; Fulton, Olivia; Le, Truc-Mai; O'Day, Diana R; Lalanne, Jean-Benoît; Domcke, Silvia; Murray, Stephen A; Aerts, Stein; Trapnell, Cole; Shendure, Jay

The lives of cells, recorded

细胞的生命历程,记录下来

Askary, Amjad; Chen, Wei; Choi, Junhong; Du, Lucia Y; Elowitz, Michael B; Gagnon, James A; Schier, Alexander F; Seidel, Sophie; Shendure, Jay; Stadler, Tanja; Tran, Martin

Massively parallel characterization of transcriptional regulatory elements

转录调控元件的大规模并行表征

Agarwal, Vikram; Inoue, Fumitaka; Schubach, Max; Penzar, Dmitry; Martin, Beth K; Dash, Pyaree Mohan; Keukeleire, Pia; Zhang, Zicong; Sohota, Ajuni; Zhao, Jingjing; Georgakopoulos-Soares, Ilias; Noble, William S; Yardımcı, Galip Gürkan; Kulakovskiy, Ivan V; Kircher, Martin; Shendure, Jay; Ahituv, Nadav

Multiplex generation and single-cell analysis of structural variants in mammalian genomes.

哺乳动物基因组结构变异的多重生成和单细胞分析

Pinglay Sudarshan, Lalanne Jean-Benoît, Daza Riza M, Kottapalli Sanjay, Quaisar Faaiz, Koeppel Jonas, Garge Riddhiman K, Li Xiaoyi, Lee David S, Shendure Jay

Efficient and highly amplified imaging of nucleic acid targets in cellular and histopathological samples with pSABER.

利用 pSABER 对细胞和组织病理样本中的核酸靶标进行高效、高度放大的成像

Attar Sahar, Browning Valentino E, Krebs Mary, Liu Yuzhen, Nichols Eva K, Tsue Ashley F, Shechner David M, Shendure Jay, Lieberman Joshua A, Schweppe Devin K, Akilesh Shreeram, Beliveau Brian J

Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks

对原代人T细胞的遗传和表观遗传筛选将候选致病性自身免疫变异与T细胞网络联系起来

Ching-Huang Ho,Maxwell A Dippel,Meghan S McQuade,LeAnn P Nguyen,Arpit Mishra,Stephan Pribitzer,Samantha Hardy,Harshpreet Chandok,Florence M Chardon,Troy A McDiarmid,Hannah A DeBerg,Jane H Buckner,Jay Shendure,Carl G de Boer,Michael H Guo,Ryan Tewhey,John P Ray

Combinatorial mapping of E3 ubiquitin ligases to their target substrates

E3泛素连接酶与其靶底物的组合映射

Chase C Suiter,Diego Calderon,David S Lee,Melodie Chiu,Shruti Jain,Florence M Chardon,Choli Lee,Riza M Daza,Cole Trapnell,Ning Zheng,Jay Shendure

Cross-species imputation and comparison of single-cell transcriptomic profiles

跨物种单细胞转录组谱的推断和比较

Zhang, Ran; Yang, Mu; Schreiber, Jacob; O'Day, Diana R; Turner, James M A; Shendure, Jay; Noble, William Stafford; Disteche, Christine M; Deng, Xinxian

Multicondition and multimodal temporal profile inference during mouse embryonic development

小鼠胚胎发育过程中多条件和多模态时间特征推断

Zhang, Ran; Qiu, Chengxiang; Filippova, Galina N; Li, Gang; Shendure, Jay; Vert, Jean-Philippe; Deng, Xinxian; Noble, William Stafford; Disteche, Christine M