日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mammalian genome writing: Unlocking new length scales for genome engineering

哺乳动物基因组编写:解锁基因组工程的新尺度

Pinglay, Sudarshan; Atwater, John T; Brosh, Ran; Shendure, Jay; Maurano, Matthew T; Boeke, Jef D

Evolutionary transfer learning enables organism-wide inference of mammalian enhancer landscapes

进化迁移学习能够对哺乳动物增强子图谱进行全生物体范围的推断

Qiu, Chengxiang; Daza, Riza M; Welsh, Ian C; Patwardhan, Rupali P; Martin, Beth K; Li, Tony; Yang, Shizhao; Kempynck, Niklas; Taylor, Megan L; Fulton, Olivia; Le, Truc-Mai; O'Day, Diana R; Lalanne, Jean-Benoît; Domcke, Silvia; Murray, Stephen A; Aerts, Stein; Trapnell, Cole; Shendure, Jay

The lives of cells, recorded

细胞的生命历程,记录下来

Askary, Amjad; Chen, Wei; Choi, Junhong; Du, Lucia Y; Elowitz, Michael B; Gagnon, James A; Schier, Alexander F; Seidel, Sophie; Shendure, Jay; Stadler, Tanja; Tran, Martin

Massively parallel characterization of transcriptional regulatory elements

转录调控元件的大规模并行表征

Agarwal, Vikram; Inoue, Fumitaka; Schubach, Max; Penzar, Dmitry; Martin, Beth K; Dash, Pyaree Mohan; Keukeleire, Pia; Zhang, Zicong; Sohota, Ajuni; Zhao, Jingjing; Georgakopoulos-Soares, Ilias; Noble, William S; Yardımcı, Galip Gürkan; Kulakovskiy, Ivan V; Kircher, Martin; Shendure, Jay; Ahituv, Nadav

Multiplex generation and single-cell analysis of structural variants in mammalian genomes.

哺乳动物基因组结构变异的多重生成和单细胞分析

Pinglay Sudarshan, Lalanne Jean-Benoît, Daza Riza M, Kottapalli Sanjay, Quaisar Faaiz, Koeppel Jonas, Garge Riddhiman K, Li Xiaoyi, Lee David S, Shendure Jay

Efficient and highly amplified imaging of nucleic acid targets in cellular and histopathological samples with pSABER.

利用 pSABER 对细胞和组织病理样本中的核酸靶标进行高效、高度放大的成像

Attar Sahar, Browning Valentino E, Krebs Mary, Liu Yuzhen, Nichols Eva K, Tsue Ashley F, Shechner David M, Shendure Jay, Lieberman Joshua A, Schweppe Devin K, Akilesh Shreeram, Beliveau Brian J

Multicondition and multimodal temporal profile inference during mouse embryonic development

小鼠胚胎发育过程中多条件和多模态时间特征推断

Zhang, Ran; Qiu, Chengxiang; Filippova, Galina N; Li, Gang; Shendure, Jay; Vert, Jean-Philippe; Deng, Xinxian; Noble, William Stafford; Disteche, Christine M

Multiplex design and discovery of proximity handles for programmable proteome editing

用于可编程蛋白质组编辑的多重设计和邻近控制点的发现

Suiter, Chase C; Ahn, Green; Chiu, Melodie; Fu, Yi; Sadre, Shayan; Simon, Jessica J; Lee, David S; Fowler, Douglas M; Maly, Dustin J; Baker, David; Shendure, Jay

Single-cell, multi-region profiling of the macaque brain across the lifespan

对猕猴大脑进行终生单细胞、多区域分析

Yang, Wei; Watkins, Kelsi L; DeCasien, Alex R; O'Neill, Mary B; Bohlen, Martin O; O'Day, Diana R; Duran, Madeleine; Qiu, Chengxiang; Meleshko, Anastasia; Vo, Anh; Menke, Melia; Calderon, Diego; Sallet, Jérôme; Higham, James P; Martínez, Melween I; Trapnell, Cole; Starita, Lea M; Montague, Michael J; Platt, Michael L; Chiou, Kenneth L; Shendure, Jay; Snyder-Mackler, Noah

Elucidating Neurodevelopmental Trajectories in Cancer with Topic Modeling: Revealing Persistent External Granule Layer Lineages in Medulloblastoma

利用主题建模阐明癌症中的神经发育轨迹:揭示髓母细胞瘤中持续存在的外部颗粒层谱系

Rajendran, Ashmitha; Haldipur, Parthiv; Arora, Sonali; Grama, Kaustubh; Subramanian, Saanvi S; Galan, Leyre Merino; Johnson, David; Aldinger, Kimberly A; Shendure, Jay; Millen, Kathleen J; Gennari, John H; Pattwell, Siobhan S