ZMYND8 preferentially binds phosphorylated EZH2 to promote a PRC2-dependent to -independent function switch in hypoxia-inducible factor-activated cancer
ZMYND8优先结合磷酸化的EZH2,从而促进缺氧诱导因子激活的癌症中PRC2依赖性向非依赖性的功能转换。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2019052118
Tang, Bo; Sun, Rui; Wang, Dejie; Sheng, Haoyue; Wei, Ting; Wang, Liguo; Zhang, Jun; Ho, Thai H; Yang, Lu; Wei, Qiang; Huang, Haojie