日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes

生理性和致病性T细胞自身反应性在1型糖尿病中汇合

Anne Eugster # ,Anna Lorenc # ,Martin Kotrulev ,Yogesh Kamra ,Manisha Goel ,Katja Steinberg-Bains ,Shereen Sabbah ,Sevina Dietz ,Ezio Bonifacio ,Mark Peakman ,Iria Gomez-Tourino

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

通过同时设计亲和力、选择性、稳定性和 FcRn 结合,实现具有优异体内疗效的 CD80 偏向性 CTLA4-Ig 融合蛋白

Julie Douthwaite, Jacques Moisan, Cyril Privezentzev, Blagoje Soskic, Shereen Sabbah, Suzanne Cohen, Andie Collinson, Elizabeth England, Catherine Huntington, Ben Kemp, Li Zhuang, Suzanne Hudak, D Gareth Rees, Debbie Goldberg, Chris Barton, Linda Chang, Inna Vainshtein, Meina Liang, Laurie Iciek, Ph

Azidothymidine Sensitizes Primary Effusion Lymphoma Cells to Kaposi Sarcoma-Associated Herpesvirus-Specific CD4+ T Cell Control and Inhibits vIRF3 Function

叠氮胸苷使原发性渗出性淋巴瘤细胞对卡波西肉瘤相关疱疹病毒特异性 CD4+ T 细胞控制敏感并抑制 vIRF3 功能

Samantha J Williamson, Samantha M Nicol, Michael Stürzl, Shereen Sabbah, Andrew D Hislop

Primary B Lymphocytes Infected with Kaposi's Sarcoma-Associated Herpesvirus Can Be Expanded In Vitro and Are Recognized by LANA-Specific CD4+ T Cells

感染卡波西肉瘤相关疱疹病毒的原代B淋巴细胞可在体外扩增,并能被LANA特异性CD4+ T细胞识别。

Samantha M Nicol ,Shereen Sabbah ,Kevin F Brulois ,Jae U Jung ,Andrew I Bell ,Andrew D Hislop

MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response

MHC II 四聚体可视化人类 CD4+ T 细胞对 Epstein-Barr 病毒感染的反应,并展示核抗原 EBNA1 反应的非典型动力学

Heather M Long, Odette L Chagoury, Alison M Leese, Gordon B Ryan, Eddie James, Laura T Morton, Rachel J M Abbott, Shereen Sabbah, William Kwok, Alan B Rickinson

Kaposi's sarcoma-associated herpesvirus-encoded viral IRF3 modulates major histocompatibility complex class II (MHC-II) antigen presentation through MHC-II transactivator-dependent and -independent mechanisms: implications for oncogenesis

卡波西肉瘤相关疱疹病毒编码的病毒 IRF3 通过 MHC-II 转录激活因子依赖性和不依赖性机制调节主要组织相容性复合体 II 类 (MHC-II) 抗原呈递:对肿瘤发生的影响

Jianmin Zuo, Andrew D Hislop, Carol S Leung, Shereen Sabbah, Martin Rowe

Clinical-grade multipotent adult progenitor cells durably control pathogenic T cell responses in human models of transplantation and autoimmunity

临床级多能成体祖细胞可在人类移植和自身免疫模型中持久控制致病性 T 细胞反应

James L Reading, Jennie H M Yang, Shereen Sabbah, Ania Skowera, Robin R Knight, Jef Pinxteren, Bart Vaes, Timothy Allsopp, Anthony E Ting, Sarah Busch, Amy Raber, Robert Deans, Timothy I M Tree