Sherouk M相关文献与解析，生知库 | 链接生命科学的每一步

Cholesterol-dependent control of endosomal escape regulates intracellular trafficking of small interfering RNA therapeutics and interactions with small molecule drugs

胆固醇依赖性内体逃逸调控小干扰RNA疗法的细胞内运输及其与小分子药物的相互作用

期刊:Journal of Pharmacology and Experimental Therapeutics

影响因子:3.8

doi:10.1016/j.jpet.2025.103802

Tawfik, Sherouk M; Giang Nguyen, Le Tra; Jin, Jing; Armanios, Beshoy; Zhong, Xiao-Bo

Impact on efficacy of target reduction of two FDA-approved ASO drugs by intracellular glucose levels in inÂ vitro cell models.

细胞内葡萄糖水平对两种 FDA 批准的 ASO 药物靶点降低的疗效在体外细胞模型中的影响

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.1

doi:10.1016/j.omtn.2025.102487

Nguyen Le Tra Giang, Tawfik Sherouk M, Jin Jing, Durwin Andrea, Zhong Xiao-Bo

细胞生物学

发表日期：2025

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Intracellular fatty acid levels differentially impact target silencing by FDA-approved siRNA drugs.

细胞内脂肪酸水平对FDA批准的siRNA药物靶向沉默的影响存在差异

期刊:Biochemical Pharmacology

影响因子:5.6

doi:10.1016/j.bcp.2025.117192

Tawfik Sherouk M, Giang Nguyen Le Tra, Jin Jing, Zhong Xiao-Bo

细胞生物学

发表日期：2025

文献求助收藏

Visualization of CYP3A4 expression at both mRNA and protein levels simultaneously at single cell resolution in various conditions using RNAscope combined with immunofluorescence.

利用 RNAscope 结合免疫荧光技术，在各种条件下以单细胞分辨率同时可视化 CYP3A4 在 mRNA 和蛋白质水平上的表达。

期刊:Drug Metabolism and Disposition

影响因子:4

doi:10.1016/j.dmd.2025.100123

Jin Jing, Tawfik Sherouk M, Nguyen Le Tra Giang, Armanios Beshoy, Zhong Xiao-Bo

The Impact of a Community Pharmacy-Led Deworming-Related Counselling Service: An Interventional Study in a Low-to-Middle Income Country

社区药房主导的驱虫相关咨询服务的影响：一项在低收入和中等收入国家开展的干预性研究

期刊:Tropical Medicine and Infectious Disease

影响因子:2.6

doi:10.3390/tropicalmed10080215

Kassem, Amira B; Al Meslamani, Ahmad Z; AbdElrahman, Mohamed; Al Mazrouei, Nadia; Okda, Sherouk M; El-Bassiouny, Noha A; Hamedo, Asmaa Abdel-Hamed; Shaban, Doaa Abdelrazek; Elsmadessy, Dina Fathy; Binsaleh, Ammena Y; Saleh, Asmaa; Moustafa, Hebatallah Ahmed Mohamed

发表日期：2025

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Indication-Specific Dosing and Dose-Evaluation Strategies in New Indications for Non-Oncology Monoclonal Antibodies

非肿瘤单克隆抗体新适应症的适应症特异性给药和剂量评估策略

期刊:Journal of Clinical Pharmacology

影响因子:2.3

doi:10.1002/jcph.70000

Tawfik, Sherouk M; Tang, Fei

Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin

利用核酸疗法靶向肝脏治疗肝源性系统性疾病

期刊:Pharmacological Reviews

影响因子:17.3

doi:10.1124/pharmrev.123.000815

Gogate, Anagha; Belcourt, Jordyn; Shah, Milan; Wang, Alicia Zongxun; Frankel, Alexis; Kolmel, Holly; Chalon, Matthew; Stephen, Prajith; Kolli, Aarush; Tawfik, Sherouk M; Jin, Jing; Bahal, Raman; Rasmussen, Theodore P; Manautou, José E; Zhong, Xiao-Bo

发表日期：2023

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Effects of Metformin Combined With Antifolates on HepG2 Cell Metabolism and Cellular Proliferation

二甲双胍联合抗叶酸药物对HepG2细胞代谢及细胞增殖的影响

期刊:Frontiers in Oncology

影响因子:3.5

doi:10.3389/fonc.2022.828988

Sherouk M Tawfik, Maha R A Abdollah, Mohey M Elmazar, Hassan A N El-Fawal, Anwar Abdelnaser

Climate change, human health, and the exposome: Utilizing OMIC technologies to navigate an era of uncertainty

气候变化、人类健康与暴露组：利用组学技术应对不确定时代

期刊:Frontiers in Public Health

影响因子:3.4

doi:10.3389/fpubh.2022.973000

Abdelzaher, Hana; Tawfik, Sherouk M; Nour, Ahmed; Abdelkader, Sarah; Elbalkiny, Shaimaa Tarek; Abdelkader, Mohamed; Abbas, Walaa A; Abdelnaser, Anwar

发表日期：2022

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Therapeutic potential of L-carnitine in coronary artery disease: a systematic review

左旋肉碱在冠状动脉疾病中的治疗潜力：系统评价

Cholesterol-dependent control of endosomal escape regulates intracellular trafficking of small interfering RNA therapeutics and interactions with small molecule drugs

胆固醇依赖性内体逃逸调控小干扰RNA疗法的细胞内运输及其与小分子药物的相互作用

Impact on efficacy of target reduction of two FDA-approved ASO drugs by intracellular glucose levels in inÂ vitro cell models.

细胞内葡萄糖水平对两种 FDA 批准的 ASO 药物靶点降低的疗效在体外细胞模型中的影响

Intracellular fatty acid levels differentially impact target silencing by FDA-approved siRNA drugs.

细胞内脂肪酸水平对FDA批准的siRNA药物靶向沉默的影响存在差异

Visualization of CYP3A4 expression at both mRNA and protein levels simultaneously at single cell resolution in various conditions using RNAscope combined with immunofluorescence.

利用 RNAscope 结合免疫荧光技术，在各种条件下以单细胞分辨率同时可视化 CYP3A4 在 mRNA 和蛋白质水平上的表达。

The Impact of a Community Pharmacy-Led Deworming-Related Counselling Service: An Interventional Study in a Low-to-Middle Income Country

社区药房主导的驱虫相关咨询服务的影响：一项在低收入和中等收入国家开展的干预性研究

Indication-Specific Dosing and Dose-Evaluation Strategies in New Indications for Non-Oncology Monoclonal Antibodies

非肿瘤单克隆抗体新适应症的适应症特异性给药和剂量评估策略

Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin

利用核酸疗法靶向肝脏治疗肝源性系统性疾病

Effects of Metformin Combined With Antifolates on HepG2 Cell Metabolism and Cellular Proliferation

二甲双胍联合抗叶酸药物对HepG2细胞代谢及细胞增殖的影响

Climate change, human health, and the exposome: Utilizing OMIC technologies to navigate an era of uncertainty

气候变化、人类健康与暴露组：利用组学技术应对不确定时代