Leptin administration to overweight and obese subjects for 6 months increases free leptin concentrations but does not alter circulating hormones of the thyroid and IGF axes during weight loss induced by a mild hypocaloric diet.

对超重和肥胖受试者进行 6 个月的瘦素治疗，可增加游离瘦素浓度，但不会改变轻度低热量饮食引起的体重减轻期间甲状腺和 IGF 轴的循环激素