日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Gambogenic acid ameliorates inflammation by inhibiting HK1-mediated Warburg effect and NLRP3 inflammasome activation in sepsis.

藤黄酸通过抑制HK1介导的Warburg效应和NLRP3炎症小体激活来减轻脓毒症中的炎症。

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2025.10.020
Pang Huanhuan, Chen Honglin, Chen Peng, Wei Xu, Liu Hongda, He Xueling, Yang Yang, Zhang Junzhe, Li Dianfei, Lou Linlin, Xie Wen, Qiu Chong, Xia Fei, Guo Qiuyan, Shen Shengnan, Shi Qiaoli, Li Weiguang, Han Guang, Wang Xijun, Wang Jigang, Xu Chengchao
炎症
炎性小体
炎症/感染
败血症
LRP3
NLRP3
炎性小体
免疫/内分泌
发表日期：2026
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Comparative Analysis of Polysaccharides from Chicory Roots and Aerial Parts Reveals Comparable Cytoprotective Effects Associated with MAPK/NF-κB Signaling

菊苣根和地上部分多糖的比较分析揭示了与 MAPK/NF-κB 信号通路相关的相似细胞保护作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27052303
Ying, Yi; Ma, Ang; Zhang, Shujie; Qiu, Wenfeng; Xuan, Hongda; Wang, Qingchun; Shi, Qiaoli; Chai, Xin; Liu, Dandan; Lyu, Hai-Ning
NF-κB
信号转导
细胞生物学
MAPK/ERK
发表日期：2026
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Covalent targeting of PSMD14 by Eupalinolide B induces oncoprotein degradation and apoptosis in acute promyelocytic leukemia cells.

Eupalinolide B 通过共价靶向 PSMD14 诱导急性早幼粒细胞白血病细胞中的癌蛋白降解和细胞凋亡。

期刊:RSC Chemical Biology
影响因子:3.1
doi:10.1039/d5cb00197h
Chu Zheng, Xu Liting, Chen Honglin, Fan Tianyun, Hu Xueqian, Wong Yin Kwan, Shi Qiaoli, Zhang Junzhe, Xu Chengchao, Wang Jigang, Tang Huan
白血病
细胞生物学
粒细胞
IDE
uPA
Apoptosis
蛋白降解
凋亡
发表日期：2026
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Rhein/Fe(3+) nanoassembly for triple-negative breast cancer treatment via a ferroptosis and immunogenic death

利用大黄素/Fe(3+)纳米组装体通过铁死亡和免疫原性死亡治疗三阴性乳腺癌

期刊:
影响因子:
doi:10.1016/j.chmed.2026.02.012
Liang, Shuntao; Gan, Licheng; Tao, Xiaomei; Xia, Fei; Tu, Qingchao; Zhong, Linying; Fu, Yuanfeng; Liu, Yinan; Meng, Yuqing; Shi, Qiaoli; Zhang, Junzhe; Wang, Jigang; Qiu, Chong
肿瘤
肿瘤免疫
铁死亡
乳腺癌
免疫/内分泌
发表日期：2026
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Multimodal lung cancer theranostics via manganese phosphate/quercetin particle

通过磷酸锰/槲皮素颗粒实现多模式肺癌诊疗一体化

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-025-02242-9
Qiu, Chong; Xia, Fei; Tu, Qingchao; Tang, Huan; Liu, Yinan; Liu, Hongda; Wang, Chen; Yao, HaiLu; Zhong, Linying; Fu, Yuanfeng; Guo, Pengbo; Chen, Weiqi; Zhou, Xinyu; Zou, Li; Gan, Licheng; Yan, Jiawei; Hou, Yichong; Zhang, Junzhe; Pang, Huanhuan; Meng, Yuqing; Shi, Qiaoli; Han, Guang; Wang, Xijun; Wang, Jigang
肺癌
肿瘤
肿瘤免疫
发表日期：2025
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Synergistic gambogic acid/Ga³⁺ remodels the immunosuppressive tumor microenvironment to enhance triple-negative breast cancer therapy

藤黄酸/Ga³⁺协同作用重塑免疫抑制性肿瘤微环境，从而增强三阴性乳腺癌的治疗效果。

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-025-03758-4
Qiu, Chong; Guo, Pengbo; Wang, Chen; Tu, Qingchao; Zhong, LinYing; Fu, Yuanfeng; Liu, Yinan; Pang, Huanhuan; Meng, Yuqing; Shi, Qiaoli; Zhang, Junzhe; Xia, Fei; Wang, Jigang
肿瘤
肿瘤免疫
乳腺癌
肿瘤微环境
免疫/内分泌
发表日期：2025
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Chloroquine Suppresses Colorectal Cancer Progression via Targeting CHKA and PFKM to inhibit the PI3K/AKT Pathway and the Warburg Effect

氯喹通过靶向CHKA和PFKM抑制PI3K/AKT通路和瓦博格效应，从而抑制结直肠癌进展。

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.101921
Liu, Yanqing; Zhu, Yongping; Gu, Liwei; Li, Kexin; Ma, Ang; Liu, Li; Meng, Yuqing; Zhang, Junzhe; Shen, Shengnan; Shi, Qiaoli; Liu, Dandan; Zhang, Xinwei; Zhang, Shujie; Chai, Xin; Gao, Peng; Xing, Jiale; Wang, Yaxu; Chen, Honglin; Liu, Rui; Du, Qingfeng; Liu, Haitao; Dai, Lingyun; Wang, Jigang
肿瘤
肠癌
肿瘤免疫
信号转导
CHKA
AKT
发表日期：2025
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Cancer Immunotherapy Based on the Bidirectional Reprogramming of the Tumor Microenvironment by a "Brakes Off/ Step on the Accelerator" Core-Shell Manganese Phosphate/siPD-L1 Modulator

基于“刹车/加速”核壳锰磷酸盐/siPD-L1调节剂对肿瘤微环境双向重编程的癌症免疫疗法

期刊:
影响因子:
doi:10.1002/EXP.70009
Xia, Fei; Lu, Yuqian; Gong, Zipeng; Tu, Qingchao; Liang, Shuntao; Wang, Chen; Yao, HaiLu; Zhong, LinYing; Fu, Yuanfeng; Guo, Pengbo; Hou, Yichong; Zhou, Xinyu; Zou, Li; Gan, Licheng; Chen, Weiqi; Yan, Jiawei; Zhang, Junzhe; Pang, Huanhuan; Meng, Yuqing; Shi, Qiaoli; Pan, Chen; Tao, Xiaomei; Wang, Jigang; Du, Qingfeng; Qiu, Chong
肿瘤
肿瘤免疫
PD-L1
肿瘤微环境
免疫/内分泌
发表日期：2025
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Caffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice.

咖啡酸作为一种强效的合成酶，通过共价靶向小鼠体内的膜联蛋白A5来缓解炎症和肺纤维化。

期刊:Exploration (Beijing)
影响因子:
doi:10.1002/EXP.20240069
Zhu Yinhua, Zhang Ying, Zhang Qianyu, Song Ping, Zhang Junzhe, Ma Ang, Wang Chen, Gao Peng, Yang Tong, Zhou Lirun, Shi Qiaoli, Wong Yin Kwan, Luo Yongting, Tang Huan, Wang Jigang
炎症/感染
Immunology/Inflammation
炎症
发表日期：2025
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STEP: profiling cellular-specific targets and pathways of bioactive small molecules in tissues via integrating single-cell transcriptomics and chemoproteomics

STEP：通过整合单细胞转录组学和化学蛋白质组学，分析组织中生物活性小分子的细胞特异性靶点和通路

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d3sc04826h
Chen, Jiayun; Chu, Zheng; Zhang, Qian; Wang, Chen; Luo, Piao; Zhang, Ying; Xia, Fei; Gu, Liwei; Wong, Yin Kwan; Shi, Qiaoli; Xu, Chengchao; Tang, Huan; Wang, Jigang
信号转导
细胞生物学
单细胞
发表日期：2024
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