SUMOylation of PPARγ by rosiglitazone prevents LPS-induced NCoR degradation mediating down regulation of chemokines expression in renal proximal tubular cells.
罗格列酮通过 SUMO 化作用使 PPARα 发生降解，从而阻止 LPS 诱导的 NCoR 降解，进而下调肾近端小管细胞中趋化因子的表达
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0079815
Lu Ying, Zhou Qiao, Shi Yongbing, Liu Jian, Zhong Fang, Hao Xu, Li Cong, Chen Nan, Wang Weiming
