日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Lenvatinib plus transarterial chemoembolization and PD-1 inhibitors as conversion therapies for unresectable intermediate-advanced hepatocellular carcinoma: a phase 2 trial and exploratory biomolecular study

乐伐替尼联合经动脉化疗栓塞术和PD-1抑制剂作为不可切除的中晚期肝细胞癌转化疗法：一项II期临床试验和探索性生物分子研究

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02498-z
Zhang, Xiaoyun; Cai, Haozheng; Peng, Wei; Wang, Haiqing; Wu, JiaYi; Zhu, Xinrui; Guo, Weixin; Xie, Fei; Zhang, Yu; Wang, Ming; Yu, Yu; Zhou, Yongjie; Li, Chuan; Shen, Junyi; Liu, Chang; Yang, Yu; Jiang, Xiaozhong; Li, Qiu; Chen, Weixia; Shi, Yujun; Lu, Wusheng; Sun, Xin; Feng, Xielin; Yan, Maolin; Cheng, Shuqun; Wen, Tianfu
细胞生物学
肿瘤
肿瘤免疫
PD-1
发表日期：2026
文献求助 收藏

Arginase 1 promotes hepatic lipogenesis by regulating ERK2/PPARγ signaling in a non-canonical manner.

精氨酸酶 1 通过非经典方式调节 ERK2/PPARα 信号通路来促进肝脏脂肪生成。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69731-3
Shao Mingyang, Cao Xiaoyue, Chen Yuwei, Zhu Ziqi, Shu Yuke, Tao Qing, Xu Qing, Ma Tingting, Wu Zhenru, Chen Menglin, Zhou Yongjie, Yao Rong, Gong Junhua, Yang Jiayin, Shi Yujun
信号转导
MAPK/ERK
发表日期：2026
文献求助 收藏

LPCAT1 and MRPL9 Promote Hepatocellular Carcinoma Progression via AKT Phosphorylation and Define a Mitochondrial Prognostic Model

LPCAT1 和 MRPL9 通过 AKT 磷酸化促进肝细胞癌进展，并构建线粒体预后模型

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers18071144
Yang, Hui; Zhu, Ziqi; Zhu, Hanwen; Li, Nanjing; Zheng, Sinian; Hu, Ling; Wu, Zhenru; Shi, Yujun
肿瘤
肿瘤免疫
信号转导
线粒体
磷酸化
细胞生物学
AKT
发表日期：2026
文献求助 收藏

Retrospective case series of peripheral neuropathy following carbon monoxide poisoning: clinical and electrophysiological characteristics

一氧化碳中毒后周围神经病变的回顾性病例系列研究：临床和电生理特征

期刊:BMC Neurology
影响因子:2.2
doi:10.1186/s12883-026-04830-8
Ma, Zongyan; Duan, Yanni; Huang, Xingxing; Lang, Yun; Li, Wen; Shi, Yujun
发表日期：2026
文献求助 收藏

KAT2A-driven succinylation of SRSF11 enforces spliceosome-mediated RAD52 splicing to promote homologous recombination and radioresistance in hepatocellular carcinoma

KAT2A驱动的SRSF11琥珀酰化增强剪接体介导的RAD52剪接，从而促进肝细胞癌中的同源重组和放射抗性。

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02458-7
Wu, Jun; Yuan, Jingsheng; Liu, Zijian; Zhou, Yongjie; Zhang, Bo; Xu, Yahong; Zeng, Qiwen; Wu, Zhenru; Kong, Lingxiang; Wang, Jiaguo; Zhang, Bohan; Yang, Jian; Lv, Tao; Shi, Yujun; Yang, Jiayin
肿瘤
琥珀酰化
肿瘤免疫
KAT2A
SRSF1
RAD52
细胞生物学
发表日期：2025
文献求助 收藏

Avian GCGR-mediated continuous fat utilization offers perspectives for obesity treatment

禽类GCGR介导的持续脂肪利用为肥胖症治疗提供了新的视角

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66305-7
Zhang, Chang; Wang, Xue; Feng, Chenxi; Zheng, Huaping; Leng, Song; Jiang, Yiheng; Sun, Qian; Li, Xiaoou; Zhang, Ting; Zhang, Jiacheng; Chen, Haidi; Lai, Shanshan; Makalowski, Wojciech; Brosius, Jürgen; Shi, Yujun; He, Yang; Hu, Peng; Sun, Qiu; Deng, Cheng
肥胖
代谢
发表日期：2025
文献求助 收藏

c-Kit(+) cells that intercalate with crypt Lgr5(+) cells are distinctively multipotent in colonic epithelium renewal and repair.

与隐窝 Lgr5(+) 细胞交错的 c-Kit(+) 细胞在结肠上皮更新和修复中具有独特的多能性

期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-025-01471-1
Xu Qing, Zeng Yuting, Jiang Lan, Zhou Yongjie, Wu Zhenru, Liu Shiyu, Men Ruoting, Li Shujun, Yang Jiayin, Huang Wei, Shi Yujun
细胞生物学
肠道菌群
发表日期：2025
文献求助 收藏

The Lactate-Primed KAT8‒PCK2 Axis Exacerbates Hepatic Ferroptosis During Ischemia/Reperfusion Injury by Reprogramming OXSM-Dependent Mitochondrial Fatty Acid Synthesis.

乳酸启动的 KAT8–€'PCK2 轴通过重编程 OXSM 依赖的线粒体脂肪酸合成，加剧缺血/再灌注损伤期间的肝脏铁死亡

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202414141
Yuan Jingsheng, Yang Mingyang, Wu Zhenru, Wu Jun, Zheng Kejie, Wang JiaGuo, Zeng Qiwen, Chen Menglin, Lv Tao, Shi Yujun, Yang Jiayin, Yang Jian
毒理研究
肝损伤
线粒体
铁死亡
发表日期：2025
文献求助 收藏

Poly (ADP-ribose) polymerase inhibitors in cancer therapy

聚（ADP-核糖）聚合酶抑制剂在癌症治疗中的应用

期刊:Chinese Medical Journal
影响因子:7.3
doi:10.1097/CM9.0000000000003471
Zhu, Ziqi; Shi, Yujun
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

HMOX1 interacts with BNIP3 to modulate neuronal ferroptosis after spinal cord ischemia-reperfusion injury via a mitophagy-dependent mechanism

HMOX1与BNIP3相互作用，通过线粒体自噬依赖性机制调节脊髓缺血再灌注损伤后的神经元铁死亡。

期刊:Cell Death Discovery
影响因子:7
doi:10.1038/s41420-025-02831-z
Duan, Yanni; Zhang, Yibao; Yang, Fengguang; Zhang, Mingtao; Shi, Yujun; Ma, Zongyan; Huang, Xingxing; Li, Wen; Lang, Yun; Hu, Xuchang; Kang, Xuewen
铁死亡
线粒体
自噬
神经科学
发表日期：2025
文献求助 收藏