Reduced expression of APC-1B but not APC-1A by the deletion of promoter 1B is responsible for familial adenomatous polyposis.
家族性腺瘤性息肉病是由启动子 1B 的缺失导致 APC-1B 表达降低,但 APC-1A 表达不降低所致
期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep26011
Yamaguchi Kiyoshi, Nagayama Satoshi, Shimizu Eigo, Komura Mitsuhiro, Yamaguchi Rui, Shibuya Tetsuo, Arai Masami, Hatakeyama Seira, Ikenoue Tsuneo, Ueno Masashi, Miyano Satoru, Imoto Seiya, Furukawa Yoichi