日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Na,K-ATPase-Fodrin-Actin Membrane Cytoskeleton Complex is Required for Endothelial Fenestra Biogenesis

Na,K-ATPase-Fodrin-肌动蛋白膜细胞骨架复合物是内皮细胞窗孔生物合成所必需的。

Ju, Meihua; Ioannidou, Sofia; Munro, Peter; Rämö, Olli; Vihinen, Helena; Jokitalo, Eija; Shima, David T

Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases

利用针对新生血管性眼病优化的双特异性CrossMAb靶向关键血管生成通路

Regula, Jörg T; Lundh von Leithner, Peter; Foxton, Richard; Barathi, Veluchamy A; Chui Ming, Gemmy Cheung; Tun, Sai Bo Bo; Wey, Yeo Sia; Iwata, Daiju; Dostalek, Miroslav; Moelleken, Jörg; Stubenrauch, Kay G; Nogoceke, Everson; Widmer, Gabriella; Strassburger, Pamela; Koss, Michael J; Klein, Christian; Shima, David T; Hartmann, Guido

Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases

利用针对新生血管性眼病优化的双特异性CrossMAb靶向关键血管生成通路

Regula, Jörg T; Lundh von Leithner, Peter; Foxton, Richard; Barathi, Veluchamy A; Gemmy Cheung, Chui Ming; Bo Tun, Sai Bo; Wey, Yeo Sia; Iwata, Daiju; Dostalek, Miroslav; Moelleken, Jörg; Stubenrauch, Kay G; Nogoceke, Everson; Widmer, Gabriella; Strassburger, Pamela; Koss, Michael J; Klein, Christian; Shima, David T; Hartmann, Guido

VEGF-A is necessary and sufficient for retinal neuroprotection in models of experimental glaucoma

在实验性青光眼模型中,VEGF-A是视网膜神经保护所必需且充分的。

Foxton, Richard H; Finkelstein, Arthur; Vijay, Sauparnika; Dahlmann-Noor, Annegret; Khaw, Peng T; Morgan, James E; Shima, David T; Ng, Yin-Shan

A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome.

A2E 通过 NLRP3 炎症小体诱导视网膜色素上皮细胞产生 IL-1β

Anderson Owen A, Finkelstein Arthur, Shima David T

VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

VE-PTP 和 VE-钙黏蛋白胞外结构域相互作用,促进磷酸化和细胞接触的调控。

Günther, Thomas; Poli, Cecilia; Müller, Judith M; Catala-Lehnen, Philip; Schinke, Thorsten; Yin, Na; Vomstein, Sandra; Amling, Michael; Schüle, Roland; Nawroth, Roman; Poell, Gregor; Ranft, Alexander; Kloep, Stephan; Samulowitz, Ulrike; Fachinger, Gregor; Golding, Matthew; Shima, David T; Deutsch, Urban; Vestweber, Dietmar

Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve

血管内皮生长因子控制神经元迁移,并与Sema3A协同作用,形成面神经的不同区域。

Schwarz, Quenten; Gu, Chenghua; Fujisawa, Hajime; Sabelko, Kimberly; Gertsenstein, Marina; Nagy, Andras; Taniguchi, Masahiko; Kolodkin, Alex L; Ginty, David D; Shima, David T; Ruhrberg, Christiana

Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis

肝素结合的 VEGF-A 提供的空间限制性模式信号控制血管分支形态发生

Ruhrberg, Christiana; Gerhardt, Holger; Golding, Matthew; Watson, Rose; Ioannidou, Sofia; Fujisawa, Hajime; Betsholtz, Christer; Shima, David T

Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion

由不同的 NSF 活性介导的 SNARE 序列解离和 GATE-16-GOS-28 复合物组装驱动高尔基体膜融合

Muller, Joyce M M; Shorter, James; Newman, Richard; Deinhardt, Katrin; Sagiv, Yuval; Elazar, Zvulun; Warren, Graham; Shima, David T