日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Versatile SMAD2 and SMAD3 epitope-tagged mouse models for genomic profiling of TGFβ signaling: Uncovering GDF9-SMAD2/3 targets

多功能SMAD2和SMAD3表位标记小鼠模型用于TGFβ信号通路基因组分析：揭示GDF9-SMAD2/3靶点

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2600071123
Liao, Zian; Zhang, Qian; Shimada, Keisuke; Nozawa, Kaori; Tang, Suni; Ikawa, Masahito; Monsivais, Diana; Matzuk, Martin M
信号转导
SMAD2
SMAD3
TGFβ
发表日期：2026
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Identification of HMCES as the Core Genetic Determinant Underlying the xhs1 Radiosensitivity Locus in LEA/LEC Rats

HMCES被鉴定为LEA/LEC大鼠xhs1放射敏感性基因座的核心遗传决定因素

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27031278
Hishida, Eisuke; Watanabe, Masaki; Sasaki, Takeru; Ashida, Tatsuya; Shimada, Keisuke; Okamura, Tadashi; Agui, Takashi; Sasaki, Nobuya
Rat
发表日期：2026
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Mouse genome engineering uncovers 18 genes dispensable for male reproduction

小鼠基因组工程揭示了18个对雄性生殖并非必需的基因

期刊:Andrology
影响因子:3.4
doi:10.1111/andr.70088
Chang, Hsin-Yi; Lu, Yonggang; Yamamoto, Kaito; Sun, Jiang; Shimada, Keisuke; Hiradate, Yuki; Fujihara, Yoshitaka; Ikawa, Masahito
Mouse
发表日期：2026
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The absence of both RIBC1 and RIBC2 induces decreased sperm motility and litter size in male mice

RIBC1和RIBC2双缺失会导致雄性小鼠精子活力下降和产仔数减少。

期刊:Andrology
影响因子:3.4
doi:10.1111/andr.70045
Katsuma, Kento; Shimada, Keisuke; Tonai, Shingo; Mashiko, Daisuke; Iida-Norita, Rie; Kaneda, Yuki; Miyata, Haruhiko; Ikawa, Masahito
发表日期：2026
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Proximity labeling of axonemal protein CFAP91 identifies EFCAB5 that regulates sperm motility

轴丝蛋白CFAP91的邻近标记鉴定出EFCAB5，该蛋白调节精子运动能力。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63705-7
Wang, Haoting; Shimada, Keisuke; Pham, Anh Hoang; Oyama, Yuki; Kamoshita, Maki; Kobayashi, Hiroko; Oura, Seiya; Yabuta, Norikazu; Ikawa, Masahito; Miyata, Haruhiko
FAP
发表日期：2025
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TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice

TEX38 将 ZDHHC19 定位到质膜，并调控小鼠精子头部形态发生。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2417943122
Kaneda, Yuki; Lu, Yonggang; Sun, Jiang; Shimada, Keisuke; Emori, Chihiro; Noda, Taichi; Koyano, Takayuki; Matsuyama, Makoto; Miyata, Haruhiko; Ikawa, Masahito
DHH
信号转导
发表日期：2025
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Compensation for X-linked Pdha1 silencing by Pdha2 is essential for meiotic double-strand break repair in spermatogenesis.

Pdha2 对 X 连锁 Pdha1 沉默的补偿对于精子发生过程中减数分裂双链断裂的修复至关重要

期刊:Development
影响因子:3.6
doi:10.1242/dev.204683
Pan Chen, Shimada Keisuke, Chang Hsin-Yi, Wang Haoting, Ikawa Masahito
其它
发表日期：2025
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CRISPR/Cas9-mediated Genome-editing Reveals 10 Testis-enriched Genes and One Non-testis-enriched Gene are Dispensable for Male Fecundity in Mice

CRISPR/Cas9介导的基因组编辑揭示，10个睾丸富集基因和1个非睾丸富集基因对小鼠雄性生育力并非必需。

期刊:Andrology
影响因子:3.4
doi:10.1111/andr.70144
Qiu, Yumiao; Shimada, Keisuke; Ikawa, Masahito
发表日期：2025
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Loss of CCDC188 causes male infertility with defects in the sperm head-neck connection in mice†

CCDC188 缺失会导致小鼠雄性不育，并伴有精子头颈连接缺陷†

期刊:Biology of Reproduction
影响因子:3
doi:10.1093/biolre/ioae137
Qiu, Yumiao; Shimada, Keisuke; Yamamoto, Kaito; Ikawa, Masahito
发表日期：2025
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Gene-deficient mouse model established by CRISPR/Cas9 system reveals 15 reproductive organ-enriched genes dispensable for male fertility

利用CRISPR/Cas9系统建立的基因缺陷小鼠模型揭示了15个在生殖器官中富集的、对雄性生育能力并非必需的基因。

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.3
doi:10.3389/fcell.2024.1411162
Nguyen, Tuyen Thi Thanh; Tokuhiro, Keizo; Shimada, Keisuke; Wang, Haoting; Mashiko, Daisuke; Tonai, Shingo; Kiyozumi, Daiji; Ikawa, Masahito
发表日期：2024
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