日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

mTOR inhibition reprograms cellular lipid homeostasis by inducing alternative lipid uptake and promoting cholesterol transport.

mTOR抑制剂通过诱导替代脂质摄取和促进胆固醇转运来重编程细胞脂质稳态。

Shin Sejeong, Han Min-Joon, Patel Ishika, Welsh Alia M, Sverdlov Maria, Cho Wonhwa, Cologna Stephanie M, Roux Philippe P, Yoon Sang-Oh

Lysosome-dependent nutrient scavenging underlies stress adaptation during epithelial-to-mesenchymal transition.

溶酶体依赖的营养物质清除是上皮间质转化过程中应激适应的基础。

Nagiec Michal J, Cavaliere Paola M, Dundar Friederike, Spencer Derrick M, Koundouros Nikolaos, Nunes Joana B, Shin Sejeong, Yoon Sang-Oh, Han Julie, Chavez Andre, Kester Olivia M, Khan Rabia, Zumbo Paul, Gardner Eric E, Parang Bobak, Mutvei Anders P, Asara John M, Gygi Steven P, Betel Doron, Dephoure Noah, Blenis John

The PIKK-AKT connection in the DNA damage response

DNA损伤反应中的PIKK-AKT连接

Shin, Sejeong; Walker, Katherine A; Yoon, Sang-Oh

ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation

ERK2通过DOCK10依赖的Rac1/FoxO1激活来调控上皮-间质可塑性。

Shin, Sejeong; Buel, Gwen R; Nagiec, Michal J; Han, Min-Joon; Roux, Philippe P; Blenis, John; Yoon, Sang-Oh

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition.

黏着斑和 IGF1R 依赖的生存和迁移途径介导肿瘤对 mTORC1/2 抑制的耐药性

Yoon Sang-Oh, Shin Sejeong, Karreth Florian A, Buel Gwen R, Jedrychowski Mark P, Plas David R, Dedhar Shoukat, Gygi Steven P, Roux Philippe P, Dephoure Noah, Blenis John

Contribution of a low-barrier hydrogen bond to catalysis is not significant in ketosteroid isomerase

低势垒氢键对酮类固醇异构酶催化的贡献并不显著

Jang, Do Soo; Choi, Gildon; Cha, Hyung Jin; Shin, Sejeong; Hong, Bee Hak; Lee, Hyeong Ju; Lee, Hee Cheon; Choi, Kwan Yong

Integrin trafficking and tumor progression

整合素转运和肿瘤进展

Shin, Sejeong; Wolgamott, Laura; Yoon, Sang-Oh

Structure of malonamidase E2 reveals a novel Ser-cisSer-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature

丙二酰胺酶E2的结构揭示了一种新的丝氨酸水解酶折叠结构,其中包含一种天然普遍存在的新型丝氨酸-顺式丝氨酸-赖氨酸催化三联体。

Shin, Sejeong; Lee, Tae-Hee; Ha, Nam-Chul; Koo, Hyun Min; Kim, So-Yeon; Lee, Heung-Soo; Kim, Yu Sam; Oh, Byung-Ha