日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Erratum: A review of clinical pharmacology considerations in antibody-drug conjugates approved by the US Food and Drug Administration between 2000 and 2025

勘误：对2000年至2025年间美国食品药品监督管理局批准的抗体药物偶联物临床药理学考虑因素的回顾

期刊:Translational and Clinical Pharmacology
影响因子:1.5
doi:10.12793/tcp.2026.34.e3
Koo, Seoyoung; Kim, Chae Yeon; Lim, Jeong Hyeon; Lee, Eunyoung; Kim, In Young; Shin, Young G; Moon, Hanlim
发表日期：2026
文献求助 收藏

Nonclinical safety evaluation and pharmacokinetics of Ab612, a novel anti-L1CAM (CD171) therapeutic antibody candidate against solid cancer

Ab612（一种新型抗L1CAM (CD171) 治疗性抗体候选药物）的非临床安全性评价和药代动力学研究，该药物可用于治疗实体瘤。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-025-04142-9
Kim, Se-Ho; Chae, Hee Su; Ko, Soo Min; Jeong, Da Som; Lee, Ji-Young; Shin, Young G; Yoon, Seon-Joo; Son, Woo-Chan
CD171
L1CAM
发表日期：2025
文献求助 收藏

Development of a Novel Immunoprecipitation Method for Extracting Monoclonal Antibodies From Brain Tissue and Its Application to Assessing In Vivo Brain Penetration in Mouse via Liquid Chromatography-Mass Spectrometry.

开发一种从脑组织中提取单克隆抗体的新型免疫沉淀方法，并通过液相色谱-质谱法评估其在小鼠体内的脑渗透性

期刊:Biomedical Chromatography
影响因子:1.7
doi:10.1002/bmc.70196
Hwang Sangsoo, Park Seo-Jin, Lim Jeong-Hyeon, Shin Young G
免疫/内分泌
Mouse
发表日期：2025
文献求助 收藏

A review of clinical pharmacology considerations in antibody-drug conjugates approved by the US Food and Drug Administration between 2000 and 2025

对2000年至2025年间美国食品药品监督管理局批准的抗体药物偶联物的临床药理学考虑因素进行回顾

期刊:Translational and Clinical Pharmacology
影响因子:1.5
doi:10.12793/tcp.2025.33.e21
Koo, Seoyoung; Kim, Chae Yeon; Lim, Jeong-Hyeon; Lee, Eunyoung; Kim, In Young; Shin, Young G; Moon, Hanlim
发表日期：2025
文献求助 收藏

Evaluation of In Vivo Prepared Albumin-Drug Conjugate Using Immunoprecipitation Linked LC-MS Assay and Its Application to Mouse Pharmacokinetic Study

利用免疫沉淀-液相色谱-质谱联用技术评价体内制备的白蛋白-药物偶联物及其在小鼠药代动力学研究中的应用

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules28073223
Lim, Jeong-Hyeon; Park, Minjae; Park, Yuri; Park, Seo-Jin; Lee, Jiyu; Hwang, Sangsoo; Lee, Jeongmin; Lee, Yujin; Jo, Eunjeong; Shin, Young G
IP
Mouse
免疫/内分泌
发表日期：2023
文献求助 收藏

Investigation of In Vitro and In Vivo Metabolism of α-Amanitin in Rats Using Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometric Method

采用液相色谱-四极杆飞行时间质谱法研究α-鹅膏蕈碱在大鼠体内和体外的代谢

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules27238612
Lee, Jiyu; Lee, Byeong Ill; Choi, Jangmi; Park, Yuri; Park, Seo-Jin; Park, Minjae; Lim, Jeong-Hyeon; Hwang, Sangsoo; Lee, Jeong-Min; Shin, Young G
Rat
代谢
发表日期：2022
文献求助 收藏

First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors

IM156（一种新型强效双胍类氧化磷酸化（OXPHOS）抑制剂）在晚期实体瘤患者中的首次人体研究

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-022-01277-9
Janku, Filip; Beom, Seung-Hoon; Moon, Yong Wha; Kim, Tae Won; Shin, Young G; Yim, Dong-Seok; Kim, Gun Min; Kim, Hyo Song; Kim, Sun Young; Cheong, Jae-Ho; Lee, Young Woo; Geiger, Barb; Yoo, Sanghee; Thurston, Archie; Welsch, Dean; Rudoltz, Marc S; Rha, Sun Young
信号转导
磷酸化
发表日期：2022
文献求助 收藏

Assessments of the In Vitro and In Vivo Linker Stability and Catabolic Fate for the Ortho Hydroxy-Protected Aryl Sulfate Linker by Immuno-Affinity Capture Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometric Assay

采用免疫亲和捕获液相色谱-四极杆飞行时间质谱法评估邻位羟基保护的芳基硫酸酯连接子的体外和体内稳定性及分解代谢命运

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics13010125
Lee, Byeong Ill; Park, Seo-Jin; Park, Yuri; Shin, Seok-Ho; Choi, Jang-Mi; Park, Min-Jae; Lim, Jeong-Hyeon; Kim, Sun Young; Lee, Hyangsook; Shin, Young G
代谢
免疫/内分泌
发表日期：2021
文献求助 收藏

In Vitro, In Silico, and In Vivo Assessments of Pharmacokinetic Properties of ZM241385

ZM241385 的药代动力学特性的体外、计算机模拟和体内评估

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules25051106
Byeon, Jin-Ju; Park, Min-Ho; Shin, Seok-Ho; Park, Yuri; Lee, Byeong Ill; Choi, Jang-Mi; Kim, Nahye; Park, Seo-Jin; Park, Min-Jae; Lim, Jeong-Hyeon; Na, Young-Guk; Shin, Young G
发表日期：2020
文献求助 收藏

Quantification of an Antibody-Conjugated Drug in Fat Plasma by an Affinity Capture LC-MS/MS Method for a Novel Prenyl Transferase-Mediated Site-Specific Antibody-Drug Conjugate

利用亲和捕获液相色谱-串联质谱法定量分析脂肪血浆中新型异戊二烯基转移酶介导的位点特异性抗体-药物偶联物中的抗体偶联药物

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules25071515
Lee, Byeong Ill; Park, Min-Ho; Byeon, Jin-Ju; Shin, Seok-Ho; Choi, Jangmi; Park, Yuri; Park, Yun-Hee; Chae, Jeiwook; Shin, Young G
发表日期：2020
文献求助 收藏