日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors

早老素介导 EphrinB 和脑源性神经营养因子的神经保护功能,并调节 EphB2 和 TrkB 受体的配体诱导内化和代谢。

Barthet, Gael; Dunys, Julie; Shao, Zhiping; Xuan, Zhao; Ren, Yimin; Xu, Jindong; Arbez, Nicolas; Mauger, Gweltas; Bruban, Julien; Georgakopoulos, Anastasios; Shioi, Junichi; Robakis, Nikolaos K

Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates.

γ-分泌酶抑制剂可稳定该复合物,并对淀粉样前体蛋白和其他底物的加工产生不同的影响

Barthet Gael, Shioi Junichi, Shao Zhiping, Ren Yimin, Georgakopoulos Anastasios, Robakis Nikolaos K

p120 catenin recruits cadherins to gamma-secretase and inhibits production of Abeta peptide.

p120 连环蛋白募集钙黏蛋白至γ-分泌酶,抑制Aβ肽的产生

Kouchi Zen, Barthet Gael, Serban Geo, Georgakopoulos Anastasios, Shioi Junichi, Robakis Nikolaos K

Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability.

钙黏蛋白介导 PS1 和 β-连环蛋白之间的结合以及 PS1 对 β-连环蛋白稳定性的影响

Serban Geo, Kouchi Zen, Baki Lia, Georgakopoulos Anastasios, Litterst Claudia M, Shioi Junichi, Robakis Nikolaos K