日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3

CBP 组蛋白乙酰转移酶抑制剂下调 p53 活化并促进组蛋白 H3 赖氨酸 27 甲基化

Adam S Vincek, Jigneshkumar Patel, Anbalagan Jaganathan, Antonia Green, Valerie Pierre-Louis, Vimal Arora, Jill Rehmann, Mihaly Mezei, Ming-Ming Zhou, Michael Ohlmeyer, Shiraz Mujtaba

Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains

针对 BET 溴结构域的强效重氮苯抑制剂的结构引导设计

Guangtao Zhang, Alexander N Plotnikov, Elena Rusinova, Tong Shen, Keita Morohashi, Jennifer Joshua, Lei Zeng, Shiraz Mujtaba, Michael Ohlmeyer, Ming-Ming Zhou

A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes

与辅激活剂 CREB 结合蛋白结合的小分子可阻断心肌细胞凋亡

Jagat C Borah, Shiraz Mujtaba, Ioannis Karakikes, Lei Zeng, Michaela Muller, Jigneshkumar Patel, Natasha Moshkina, Keita Morohashi, Weijia Zhang, Guillermo Gerona-Navarro, Roger J Hajjar, Ming-Ming Zhou

p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylase

p53 诱导的生长停滞受线粒体 SirT3 去乙酰化酶调控

SiDe Li, Michaela Banck, Shiraz Mujtaba, Ming-Ming Zhou, Mary M Sugrue, Martin J Walsh