日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env

结构动力学揭示 HIV 包膜上中和表位的分离株特异性差异

Edgar A Hodge, Gajendra S Naika, Sally M Kephart, Adam Nguyen, Richard Zhu, Mark A Benhaim, Wenjin Guo, John P Moore, Shiu-Lok Hu, Rogier W Sanders, Kelly K Lee

In vivo Serial Passaging of Human-Simian Immunodeficiency Virus Clones Identifies Characteristics for Persistent Viral Replication

人-猴免疫缺陷病毒克隆的体内连续传代培养揭示了病毒持续复制的特征

Thippeshappa, Rajesh; Polacino, Patricia; Chandrasekar, Shaswath S; Truong, Khanghy; Misra, Anisha; Aulicino, Paula C; Hu, Shiu-Lok; Kaushal, Deepak; Kimata, Jason T

Gene Transfer in Adeno-Associated Virus Seropositive Rhesus Macaques Following Rapamycin Treatment and Subcutaneous Delivery of AAV6, but Not Retargeted AAV6 Vectors

雷帕霉素治疗和皮下注射AAV6后,腺相关病毒血清阳性恒河猴体内发生基因转移,但重新靶向的AAV6载体则不发生基因转移

Daniel Stone ,Elizabeth J Kenkel ,Michelle A Loprieno ,Motoko Tanaka ,Harshana S De Silva Feelixge ,Arjun J Kumar ,Laurence Stensland ,Willimark M Obenza ,Solomon Wangari ,Chul Y Ahrens ,Robert D Murnane ,Christopher W Peterson ,Hans-Peter Kiem ,Meei-Li Huang ,Martine Aubert ,Shiu-Lok Hu ,Keith R Jerome

Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Syrian hamsters

基于痘苗病毒的疫苗可使叙利亚仓鼠获得针对SARS-CoV-2病毒的保护性免疫力。

Rakesh Kulkarni ,Wen-Ching Chen ,Ying Lee ,Chi-Fei Kao ,Shiu-Lok Hu ,Hsiu-Hua Ma ,Jia-Tsrong Jan ,Chun-Che Liao ,Jian-Jong Liang ,Hui-Ying Ko ,Cheng-Pu Sun ,Yin-Shoiou Lin ,Yu-Chiuan Wang ,Sung-Chan Wei ,Yi-Ling Lin ,Che Ma ,Yu-Chan Chao ,Yu-Chi Chou ,Wen Chang

Immunization by exposure to live virus (SIVmne/HIV-2287) during antiretroviral drug prophylaxis may reduce risk of subsequent viral challenge

在接受抗逆转录病毒药物预防治疗期间,通过接触活病毒(SIVmne/HIV-2287)进行免疫接种,可能降低后续病毒攻击的风险。

Frenkel, Lisa M; Kuller, LaRene; Beck, Ingrid A; Tsai, Che-Chung; Joy, Jaimy P; Mulvania, Thera M; Hu, Shiu-Lok; Montefiori, David C; Anderson, David M

Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques

HIV-1核苷修饰mRNA疫苗在兔和恒河猴中的特性分析

Pardi, Norbert; LaBranche, Celia C; Ferrari, Guido; Cain, Derek W; Tombácz, István; Parks, Robert J; Muramatsu, Hiromi; Mui, Barbara L; Tam, Ying K; Karikó, Katalin; Polacino, Patricia; Barbosa, Christopher J; Madden, Thomas D; Hope, Michael J; Haynes, Barton F; Montefiori, David C; Hu, Shiu-Lok; Weissman, Drew

Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation

MHC单倍体相合造血干细胞移植后早期SHIV病毒库持续存在的证据

Lucrezia Colonna ,Christopher W Peterson ,John B Schell ,Judith M Carlson ,Victor Tkachev ,Melanie Brown ,Alison Yu ,Sowmya Reddy ,Willi M Obenza ,Veronica Nelson ,Patricia S Polacino ,Heather Mack ,Shiu-Lok Hu ,Katie Zeleski ,Michelle Hoffman ,Joe Olvera ,Scott N Furlan ,Hengqi Zheng ,Agne Taraseviciute ,Daniel J Hunt ,Kayla Betz ,Jennifer F Lane ,Keith Vogel ,Charlotte E Hotchkiss ,Cassie Moats ,Audrey Baldessari ,Robert D Murnane ,Christopher English ,Cliff A Astley ,Solomon Wangari ,Brian Agricola ,Joel Ahrens ,Naoto Iwayama ,Andrew May ,Laurence Stensland ,Meei-Li W Huang ,Keith R Jerome ,Hans-Peter Kiem ,Leslie S Kean

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

核苷修饰的mRNA疫苗可诱导强效的滤泡辅助性T细胞和生发中心B细胞反应

Pardi Norbert, Hogan Michael J, Naradikian Martin S, Parkhouse Kaela, Cain Derek W, Jones Letitia, Moody M Anthony, Verkerke Hans P, Myles Arpita, Willis Elinor, LaBranche Celia C, Montefiori David C, Lobby Jenna L, Saunders Kevin O, Liao Hua-Xin, Korber Bette T, Sutherland Laura L, Scearce Richard M, Hraber Peter T, Tombácz István, Muramatsu Hiromi, Ni Houping, Balikov Daniel A, Li Charles, Mui Barbara L, Tam Ying K, Krammer Florian, Karikó Katalin, Polacino Patricia, Eisenlohr Laurence C, Madden Thomas D, Hope Michael J, Lewis Mark G, Lee Kelly K, Hu Shiu-Lok, Hensley Scott E, Cancro Michael P, Haynes Barton F, Weissman Drew

Intestinal damage precedes mucosal immune dysfunction in SIV infection

在SIV感染中,肠道损伤先于黏膜免疫功能障碍出现。

Hensley-McBain, Tiffany; Berard, Alicia R; Manuzak, Jennifer A; Miller, Charlene J; Zevin, Alexander S; Polacino, Patricia; Gile, Jillian; Agricola, Brian; Cameron, Mark; Hu, Shiu-Lok; Estes, Jacob D; Reeves, R Keith; Smedley, Jeremy; Keele, Brandon F; Burgener, Adam D; Klatt, Nichole R

Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy

移植对周围组织和组织相关病毒库的不同影响:对艾滋病基因治疗的启示

Peterson, Christopher W; Wang, Jianbin; Deleage, Claire; Reddy, Sowmya; Kaur, Jasbir; Polacino, Patricia; Reik, Andreas; Huang, Meei-Li; Jerome, Keith R; Hu, Shiu-Lok; Holmes, Michael C; Estes, Jacob D; Kiem, Hans-Peter