日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms

胰腺导管腺癌 (PDAC) 中不同的免疫细胞浸润模式表现出不同的免疫细胞选择和免疫抑制机制。

Shivan Sivakumar # ,Ashwin Jainarayanan # ,Edward Arbe-Barnes # ,Piyush Kumar Sharma # ,Maire Ni Leathlobhair # ,Sakina Amin # ,David J Reiss # ,Lara Heij ,Samarth Hegde ,Assaf Magen ,Felicia Tucci ,Bo Sun ,Shihong Wu ,Nithishwer Mouroug Anand ,Hubert Slawinski ,Santiago Revale ,Isar Nassiri ,Jonathon Webber ,Gerard D Hoeltzel ,Adam E Frampton ,Georg Wiltberger ,Ulf Neumann ,Philip Charlton ,Laura Spiers ,Tim Elliott ,Maria Wang ,Suzana Couto ,Thomas Lila ,Pallavur V Sivakumar ,Alexander V Ratushny ,Mark R Middleton ,Dimitra Peppa ,Benjamin Fairfax ,Miriam Merad ,Michael L Dustin ,Enas Abu-Shah ,Rachael Bashford-Rogers

Unlocking the diagnostic power of plasma extracellular vesicle miR-200 family in pancreatic ductal adenocarcinoma

解锁血浆细胞外囊泡 miR-200 家族在胰腺导管腺癌中的诊断能力

Daniel S K Liu #, Jisce R Puik #, Bhavik Y Patel, Morten T Venø, Mahrou Vahabi, Mireia Mato Prado, Jason P Webber, Eleanor Rees, Flora M Upton, Kate Bennett, Catherine Blaker, Benoit Immordino, Annalisa Comandatore, Luca Morelli, Shivan Sivakumar, Rutger-Jan Swijnenburg, Marc G Besselink, Long R Jia

Tissue-resident natural killer cells support survival in pancreatic cancer through promotion of cDC1-CD8 T activity

组织驻留自然杀伤细胞通过促进cDC1-CD8 T细胞活性来支持胰腺癌细胞的存活。

Simei Go # ,Constantinos Demetriou # ,Giampiero Valenzano # ,Sophie Hughes ,Simone Lanfredini ,Helen Ferry ,Edward Arbe-Barnes ,Shivan Sivakumar ,Rachel Bashford-Rogers ,Mark R Middleton ,Somnath Mukherjee ,Jennifer Morton ,Keaton Jones ,Eric O Neill

Pseudotime dynamics of T cells in pancreatic ductal adenocarcinoma inform distinct functional states within the regulatory and cytotoxic T cells

胰腺导管腺癌中 T 细胞的拟时间动态表明调节性和细胞毒性 T 细胞内的不同功能状态

Ashwin Jainarayanan, Nithishwer Mouroug-Anand, Edward H Arbe-Barnes, Adam J Bush, Rachael Bashford-Rogers, Adam Frampton, Lara Heij, Mark Middleton, Michael L Dustin, Enas Abu-Shah, Shivan Sivakumar

Cell-free DNA TAPS provides multimodal information for early cancer detection

游离DNA TAPS为早期癌症检测提供多模态信息

Paulina Siejka-Zielińska, Jingfei Cheng, Felix Jackson, Yibin Liu, Zahir Soonawalla, Srikanth Reddy, Michael Silva, Luminita Puta, Misti Vanette McCain, Emma L Culver, Noor Bekkali, Benjamin Schuster-Böckler, Pier Francesco Palamara, Derek Mann, Helen Reeves, Eleanor Barnes, Shivan Sivakumar, Chun-X

Activated Regulatory T-Cells, Dysfunctional and Senescent T-Cells Hinder the Immunity in Pancreatic Cancer

激活的调节性 T 细胞、功能失调和衰老的 T 细胞阻碍胰腺癌的免疫力

Shivan Sivakumar, Enas Abu-Shah, David J Ahern, Edward H Arbe-Barnes, Ashwin K Jainarayanan, Nagina Mangal, Srikanth Reddy, Aniko Rendek, Alistair Easton, Elke Kurz, Michael Silva, Zahir Soonawalla, Lara R Heij, Rachael Bashford-Rogers, Mark R Middleton, Michael L Dustin