日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Advancing Preclinical Biology for Ewing Sarcoma: An International Effort

推进尤文氏肉瘤的临床前生物学研究:一项国际合作

Dela Cruz, Filemon S; Stewart, Elizabeth A; Surdez, Didier; Daley, Jessica D; Soragni, Alice; Tomazou, Eleni M; Alvarez-Perez, Jaime; Feinberg, Tamar Y; Amatruda, James F; Ganapathi, Shireen S; Ohm, Joyce E; Heske, Christine M; Cohen-Gogo, Sarah; Pesic, Dusan; Nash, Joshua O; Shlien, Adam; Roundhill, Elizabeth A; Burchill, Susan A; Crompton, Brian D; Lawlor, Elizabeth R; Loeb, David M; Delattre, Olivier; Mora, Jaume; Scotlandi, Katia; Reed, Damon R; Grohar, Patrick J; Grünewald, Thomas G P; Kovar, Heinrich; Bailey, Kelly M

ROME, an Ancient Gene with a Novel Function in Vertebrates, Is a Key Modulator of Embryonal Development and Cancer Metastasis.

ROME 是一种古老的基因,在脊椎动物中具有新的功能,是胚胎发育和癌症转移的关键调节因子。

Molotkova Anna, Deniz Emre, Swift Matthew, Glasgow Eric, Ma Junfeng, Petro Jeffrey A, Frye Isabel, Ozdemirli Metin, Pesic Dusan, Ahern Gerard P, Suter Robert K, Tiwari Purushottam B, Shlien Adam, Toretsky Jeffrey, Üren Aykut

Assessing the diagnostic impact of blood transcriptome profiling in a pediatric cohort previously assessed by genome sequencing

评估血液转录组分析对先前已通过基因组测序评估的儿科队列的诊断价值

Hou, Huayun; Yuki, Kyoko E; Costain, Gregory; Szuto, Anna; Barnes, Sierra; Ramani, Arun K; Celik, Alper; Braga, Michael; Gloven-Brown, Meagan; Stavropoulos, Dimitri J; Bowdin, Sarah; Cohn, Ronald D; Mendoza-Londono, Roberto; Scherer, Stephen W; Brudno, Michael; Marshall, Christian R; Stephen Meyn, M; Shlien, Adam; Dowling, James J; Wilson, Michael D; Kyriakopoulou, Lianna

Cell-free DNA from germline TP53 mutation carriers reflect cancer-like fragmentation patterns

来自生殖系TP53突变携带者的游离DNA反映了类似癌症的片段化模式

Wong, Derek; Tageldein, Maha; Luo, Ping; Ensminger, Erik; Bruce, Jeffrey; Oldfield, Leslie; Gong, Haifan; Fischer, Nicholas William; Laverty, Brianne; Subasri, Vallijah; Davidson, Scott; Khan, Reem; Villani, Anita; Shlien, Adam; Kim, Raymond H; Malkin, David; Pugh, Trevor J

Inter-chromosomal contacts demarcate genome topology along a spatial gradient

染色体间接触沿空间梯度划分基因组拓扑结构

Milad Mokhtaridoost, Jordan J Chalmers, Marzieh Soleimanpoor, Brandon J McMurray, Daniella F Lato, Son C Nguyen, Viktoria Musienko, Joshua O Nash, Sergio Espeso-Gil, Sameen Ahmed, Kate Delfosse, Jared W L Browning, A Rasim Barutcu, Michael D Wilson, Thomas Liehr, Adam Shlien, Samin Aref, Eric F Joyc

Spontaneous expression of the CIC::DUX4 fusion oncoprotein from a conditional allele potently drives sarcoma formation in genetically engineered mice

在基因工程小鼠中,条件性等位基因自发表达的CIC::DUX4融合癌蛋白能够有效驱动肉瘤的形成。

Hendrickson, Peter G; Oristian, Kristianne M; Browne, MaKenna R; Luo, Lixia; Ma, Yan; Cardona, Diana M; Nash, Joshua O; Ballester, Pedro L; Davidson, Scott; Shlien, Adam; Linardic, Corinne M; Kirsch, David G

Genomic and clinical characterization of a familial GIST kindred intolerant to imatinib

对伊马替尼不耐受的家族性胃肠道间质瘤家系进行基因组和临床特征分析

Ingley, K M; Zatzman, M; Fontebasso, A M; Lo, W; Subasri, V; Goldenberg, A; Li, Y; Davidson, S; Kanwar, N; Waldman, L; Brunga, L; Babichev, Y; Demicco, E G; Gupta, A; Szybowska, M; Thipphavong, S; Malkin, D; Villani, A; Shlien, A; Gladdy, R A; Kim, R H

A systematic assessment of the impact of rare canonical splice site variants on splicing using functional and in silico methods

利用功能和计算机模拟方法系统地评估罕见经典剪接位点变异对剪接的影响

Oh, Rachel Y; AlMail, Ali; Cheerie, David; Guirguis, George; Hou, Huayun; Yuki, Kyoko E; Haque, Bushra; Thiruvahindrapuram, Bhooma; Marshall, Christian R; Mendoza-Londono, Roberto; Shlien, Adam; Kyriakopoulou, Lianna G; Walker, Susan; Dowling, James J; Wilson, Michael D; Costain, Gregory

miR-34a is a tumor suppressor in zebrafish and its expression levels impact metabolism, hematopoiesis and DNA damage

miR-34a 是斑马鱼的肿瘤抑制因子,其表达水平影响代谢、造血和 DNA 损伤

Sergey V Prykhozhij, Kevin Ban, Zane L Brown, Kim Kobar, Gabriel Wajnberg, Charlotte Fuller, Simi Chacko, Jacynthe Lacroix, Nicolas Crapoulet, Craig Midgen, Adam Shlien, David Malkin, Jason N Berman

Genomic Microsatellite Signatures Identify Germline Mismatch Repair Deficiency and Risk of Cancer Onset

基因组微卫星特征可识别生殖系错配修复缺陷和癌症发病风险

Chung, Jiil; Negm, Logine; Bianchi, Vanessa; Stengs, Lucie; Das, Anirban; Liu, Zhihui Amy; Sudhaman, Sumedha; Aronson, Melyssa; Brunga, Ledia; Edwards, Melissa; Forster, Victoria; Komosa, Martin; Davidson, Scott; Lees, Jodi; Tomboc, Patrick; Samuel, David; Farah, Roula; Bendel, Anne; Knipstein, Jeffrey; Schneider, Kami Wolfe; Reschke, Agnes; Zelcer, Shayna; Zorzi, Alexandra; McWilliams, Robert; Foulkes, William D; Bedgood, Raymond; Peterson, Lindsay; Rhode, Sara; Van Damme, An; Scheers, Isabelle; Gardner, Sharon; Robbins, Gabriel; Vanan, Magimairajan Issai; Meyn, M Stephen; Auer, Rebecca; Leach, Brandie; Burke, Carol; Villani, Anita; Malkin, David; Bouffet, Eric; Huang, Annie; Taylor, Michael D; Durno, Carol; Shlien, Adam; Hawkins, Cynthia; Getz, Gad; Maruvka, Yosef E; Tabori, Uri