日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SUN-482 Nitric Oxide Induces Spexin (Spx), Galanin Receptor 2 (GalR2), and Galanin Receptor 3 (GalR3) mRNA Independently of the cGMP/PKG Pathway and Enhances C/EBP-β Binding to the Spx 5’ Regulatory Region

SUN-482 一氧化氮可独立于 cGMP/PKG 通路诱导 Spexin (Spx)、Galanin 受体 2 (GalR2) 和 Galanin 受体 3 (GalR3) mRNA 的表达,并增强 C/EBP-β 与 Spx 5' 调控区的结合。

Aluisio, Leah; Fraser, Ian; Berdyyeva, Tamara; Tryputsen, Volha; Shireman, Brock T; Shoblock, James; Lovenberg, Timothy; Dugovic, Christine; Bonaventure, Pascal; Tran, Andy; Belsham, Denise

Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567

新型中枢通透性 P2X7 受体拮抗剂 JNJ-47965567 的药理学表征

Anindya Bhattacharya, Qi Wang, Hong Ao, James R Shoblock, Brian Lord, Leah Aluisio, Ian Fraser, Diane Nepomuceno, Robert A Neff, Natalie Welty, Timothy W Lovenberg, Pascal Bonaventure, Alan D Wickenden, Michael A Letavic

Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission

通过药物阻断血清素 5-HT₇ 受体,可使皮质谷氨酸神经传递正常化,从而逆转大鼠的工作记忆缺陷

Pascal Bonaventure, Leah Aluisio, James Shoblock, Jamin D Boggs, Ian C Fraser, Brian Lord, Timothy W Lovenberg, Ruggero Galici

The pharmacology of Ro 64-6198, a systemically active, nonpeptide NOP receptor (opiate receptor-like 1, ORL-1) agonist with diverse preclinical therapeutic activity

Ro 64-6198 是一种具有全身活性、非肽类 NOP 受体(阿片受体样 1,ORL-1)激动剂,具有多种临床前治疗活性。本文研究了其药理学特性。

Shoblock, James R