The Cyclin C-CDK8/19 Mediator kinase module controls PRCC-TFE3 driven senescence in renal epithelium and tumorigenesis in TFE3-RCC
细胞周期蛋白C-CDK8/19介导激酶模块控制PRCC-TFE3驱动的肾上皮细胞衰老和TFE3-RCC的肿瘤发生。
期刊:Neoplasia
影响因子:7.7
doi:10.1016/j.neo.2026.101296
Kuroda, Shoichiro; Funasaki, Shintaro; Nishizawa, Hidekazu; Schmidt, Laura S; Kurahashi, Ryoma; Ito, Takaaki; Arima, Yuichiro; Tanaka, Miwa; Kitada, Atsuya; James, Amy M; Hasumi, Hisashi; Jikuya, Ryosuke; Makiyama, Kazuhide; Kurotaki, Daisuke; Minami, Takashi; Difilippantonio, Simone; Linehan, W Marston; Oike, Yuichi; Sawa, Tomohiro; Tanaka, Yasuhito; Suda, Toshio; Yokokawa, Ryuji; Nakamura, Takuro; Baba, Masaya; Kamba, Tomomi
肿瘤
肿瘤免疫
上皮细胞
信号转导
细胞衰老
CDK8
TFE3
衰老
细胞生物学
