日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Androgen receptor expression and immune characteristics of HER2-low metastatic triple-negative breast cancer

HER2低表达转移性三阴性乳腺癌的雄激素受体表达和免疫特征

Tarantino, Paolo; Cha, Jaeyoon; Binboga Kurt, Busem; Chu, Xiangying; Jovanović, Bojana; Zhou, Andrew; Hughes, Melissa; Russo, Douglas; DiLullo, Molly; Wrabel, Eileen; Jeselsohn, Rinath; Lin, Nancy U; Carter, Jamie; Chen, Yisang Serenity; Li, Tianyu; Tayob, Nabihah; Mittendorf, Elizabeth A; Schnitt, Stuart J; Goel, Shom; Tolaney, Sara M

Correction: INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

更正:INX-315,一种选择性 CDK2 抑制剂,可诱导实体瘤细胞周期停滞和衰老。

Dietrich, Catherine; Trub, Alec; Ahn, Antonio; Taylor, Michael; Ambani, Krutika; Chan, Keefe T; Lu, Kun-Hui; Mahendra, Christabella A; Blyth, Catherine; Coulson, Rhiannon; Ramm, Susanne; Watt, April C; Matsa, Sunil Kumar; Bisi, John; Strum, Jay; Roberts, Patrick; Goel, Shom

Phase I study of ribociclib (CDK4/6 inhibitor) with spartalizumab (PD-1 inhibitor) with and without fulvestrant in metastatic hormone receptor-positive breast cancer or advanced ovarian cancer

一项针对转移性激素受体阳性乳腺癌或晚期卵巢癌患者的I期研究,评估了ribociclib(CDK4/6抑制剂)联合spartalizumab(PD-1抑制剂)以及单独使用或不联合fulvestrant的疗效。

Ana C Garrido-Castro ,Noah Graham ,Lestat R Ali ,Christina Herold ,Jennifer Desrosiers ,Khanh Do ,Heather Parsons ,Tianyu Li ,Shom Goel ,Molly DiLullo ,Eileen Wrabel ,Amy J Williams ,Joyce F Liu ,Elizabeth A Mittendorf ,Stephanie K Dougan ,Nabihah Tayob ,Geoffrey I Shapiro ,Sara M Tolaney

Phase I study of ribociclib (CDK4/6 inhibitor) with spartalizumab (PD-1 inhibitor) with and without fulvestrant in metastatic hormone receptor-positive breast cancer or advanced ovarian cancer

一项针对转移性激素受体阳性乳腺癌或晚期卵巢癌患者的I期研究,评估了ribociclib(CDK4/6抑制剂)联合spartalizumab(PD-1抑制剂)以及单独使用或不联合fulvestrant的疗效。

Ana C Garrido-Castro ,Noah Graham,Lestat R Ali,Christina Herold ,Jennifer Desrosiers,Khanh Do,Heather Parsons ,Tianyu Li,Shom Goel ,Molly DiLullo,Eileen Wrabel,Amy J Williams,Joyce F Liu,Elizabeth A Mittendorf ,Stephanie K Dougan,Nabihah Tayob,Geoffrey I Shapiro,Sara M Tolaney

A Phase II Study of Abemaciclib for Patients with Retinoblastoma-Positive, Metastatic Triple-Negative Breast Cancer

一项针对视网膜母细胞瘤阳性、转移性三阴性乳腺癌患者的阿贝西利II期研究

Goel, Shom; Jovanović, Bojana; Chu, Xiangying; Hughes, Melissa; Erick, Timothy K; Russo, Douglas; DiLullo, Molly; Wrabel, Eileen; Jeselsohn, Rinath; Lin, Nancy U; Tayob, Nabihah; Mittendorf, Elizabeth; Schnitt, Stuart; Tolaney, Sara M

Comparative transcriptomic analysis of retinal response to diverse cellular stresses reveals relative contributions of different cell death processes and signalling networks

对视网膜应对多种细胞应激的转录组进行比较分析,揭示了不同细胞死亡过程和信号网络的相对贡献。

Sarkar, Subhradeep; Kannan, Ramaraj; Panigrahi, Trailokyanath; Veeramani, Karthickraja; Mb, Thirumalesh; Shanker Bhattacharya, Shom; Ghosh, Arkasubhra

INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

INX-315 是一种选择性 CDK2 抑制剂,可诱导实体瘤细胞周期停滞和衰老。

Catherine Dietrich # ,Alec Trub # ,Antonio Ahn ,Michael Taylor ,Krutika Ambani ,Keefe T Chan ,Kun-Hui Lu ,Christabella A Mahendra ,Catherine Blyth ,Rhiannon Coulson ,Susanne Ramm ,April C Watt ,Sunil Kumar Matsa ,John Bisi ,Jay Strum ,Patrick Roberts ,Shom Goel

The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects

CD8+ T细胞耐受检查点触发一种独特的细胞分化状态,该状态的特征是蛋白质翻译缺陷。

Willem Van Der Byl,Simone Nüssing,Timothy J Peters,Antonio Ahn,Hanjie Li,Guy Ledergor,Eyal David,Andrew S Koh,Mayura V Wagle,Christian Deo T Deguit,Maria N de Menezes,Avraham Travers,Shienny Sampurno,Kelly M Ramsbottom,Rui Li,Axel Kallies,Paul A Beavis,Ralf Jungmann,Maartje M C Bastings,Gabrielle T Belz,Shom Goel,Joseph A Trapani,Gerald R Crabtree,Howard Y Chang,Ido Amit,Chris C Goodnow,Fabio Luciani,Ian A Parish

The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects

CD8+ T细胞耐受检查点触发一种独特的细胞分化状态,该状态的特征是蛋白质翻译缺陷。

Willem Van Der Byl ,Simone Nüssing ,Timothy J Peters ,Antonio Ahn ,Hanjie Li ,Guy Ledergor ,Eyal David ,Andrew S Koh ,Mayura V Wagle ,Christian Deo T Deguit ,Maria N de Menezes ,Avraham Travers ,Shienny Sampurno ,Kelly M Ramsbottom ,Rui Li ,Axel Kallies ,Paul A Beavis ,Ralf Jungmann ,Maartje M C Bastings ,Gabrielle T Belz ,Shom Goel ,Joseph A Trapani ,Gerald R Crabtree ,Howard Y Chang ,Ido Amit ,Chris C Goodnow ,Fabio Luciani ,Ian A Parish

Intracellular zinc protects tumours from T cell-mediated cytotoxicity

细胞内锌可保护肿瘤免受T细胞介导的细胞毒性作用

Lelliott, Emily J; Naddaf, Jonathan; Ganio, Katherine; Michie, Jessica; Wang, Shelly; Liu, Lin; Silke, Natasha; Ahn, Antonio; Ramsbottom, Kelly M; Brennan, Amelia J; Freeman, Andrew J; Goel, Shom; Vervoort, Stephin J; Kearney, Conor J; Beavis, Paul A; McDevitt, Christopher A; Silke, John; Oliaro, Jane